4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

CAS号：15676-19-4

英文名：4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

分子式：C12H13N5O3

分子量：275.263

合成路线

三正丁基锡氰化物

三正丁基锡氰化物

7-deaza-2'-deoxy-7-iodoadenosine

7-deaza-2'-deoxy-7-iodoadenosine

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

（2R，3S，5R）-5-（4-氨基-7H-吡咯[2,3-D]嘧啶-7-基-2 -（羟甲基）四氢呋喃-3-醇

（2R，3S，5R）-5-（4-氨基-7H-吡咯[2,3-D]嘧啶-7-基-2 -（羟甲基）四氢呋喃-3-醇

2-氨基-5-溴-1H-吡咯-3,4-二甲腈

2-氨基-5-溴-1H-吡咯-3,4-二甲腈

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

ethyl N-(5-bromo-3,4-dicyano-1H-pyrrol-2-yl)methanimidate

ethyl N-(5-bromo-3,4-dicyano-1H-pyrrol-2-yl)methanimidate

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

氰化亚铜

7-deaza-2'-deoxy-7-iodoadenosine

7-deaza-2'-deoxy-7-iodoadenosine

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile

上游原料

7-deaza-2'-deoxy-7-iodoadenosine 氰化亚铜 ethyl N-(5-bromo-3,4-dicyano-1H-pyrrol-2-yl)methanimidate 三正丁基锡氰化物 2-氨基-5-溴-1H-吡咯-3,4-二甲腈

下游产品

2'-脱氧桑吉瓦霉素