百科

(S)-N-(2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl)-N-(2-hydroxyethyl)-5-(4-methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxamide

(S)-N-(2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl)-N-(2-hydroxyethyl)-5-(4-methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxamide

CAS号：1587728-01-5

英文名：(S)-N-(2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl)-N-(2-hydroxyethyl)-5-(4-methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxamide

分子式：C20H28N4O4Si

分子量：416.546

合成路线

(S)-1-chloro-2-hydroxy-5-trimethylsilyl-4-pentyne

(S)-1-chloro-2-hydroxy-5-trimethylsilyl-4-pentyne

(S)-N-(2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl)-N-(2-hydroxyethyl)-5-(4-methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxamide

(S)-N-(2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl)-N-(2-hydroxyethyl)-5-(4-methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxamide

上游原料

(S)-1-chloro-2-hydroxy-5-trimethylsilyl-4-pentyne

下游产品

2-({(2S,5R)-5-[3,5-difluoro-4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione 2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione