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2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

CAS号：1587728-03-7

英文名：2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

分子式：C17H18N4O3

分子量：326.35

合成路线

(S)-1-chloro-2-hydroxy-5-trimethylsilyl-4-pentyne

(S)-1-chloro-2-hydroxy-5-trimethylsilyl-4-pentyne

2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

2-[(2S)-2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

2-[(2S)-2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

(S)-N-(2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl)-N-(2-hydroxyethyl)-5-(4-methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxamide

(S)-N-(2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl)-N-(2-hydroxyethyl)-5-(4-methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxamide

2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

2-[(2S)-2-hydroxypent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione

上游原料

2-[(2S)-2-hydroxy-5-(trimethylsilyl)pent-4-yn-1-yl]-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione (S)-1-chloro-2-hydroxy-5-trimethylsilyl-4-pentyne

下游产品

2-({(2S,5R)-5-[3,5-difluoro-4-(trifluoromethyl)phenyl]tetrahydrofuran-2-yl}methyl)-7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione