百科

2-((S)-1-((R)-2-((S)-1-(2-(2-((S)-1-((tert-butoxycarbonyl)-L-leucyl)pyrrolidin-2-yl)thiazol-4-yl)oxazole-4-carbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)ethyl)thiazole-4-carboxylic acid

CAS号：1588428-18-5

英文名：2-((S)-1-((R)-2-((S)-1-(2-(2-((S)-1-((tert-butoxycarbonyl)-L-leucyl)pyrrolidin-2-yl)thiazol-4-yl)oxazole-4-carbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)ethyl)thiazole-4-carboxylic acid

分子式：C42H52N8O9S2

分子量：877.04

合成路线

96929-06-5

ethyl 2-<(S)-1-(N-t-butoxycarbonyl)aminoethyl>thiazole-4-carboxylate

1588428-18-5

2-((S)-1-((R)-2-((S)-1-(2-(2-((S)-1-((tert-butoxycarbonyl)-L-leucyl)pyrrolidin-2-yl)thiazol-4-yl)oxazole-4-carbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)ethyl)thiazole-4-carboxylic acid

1361053-60-2

methyl (2-(2-((S)-1-((tert-butoxycarbonyl)-L-leucyl)pyrrolidin-2-yl)thiazol-4-yl)oxazole-4-carbonyl)-L-prolinate

1588428-18-5

2-((S)-1-((R)-2-((S)-1-(2-(2-((S)-1-((tert-butoxycarbonyl)-L-leucyl)pyrrolidin-2-yl)thiazol-4-yl)oxazole-4-carbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)ethyl)thiazole-4-carboxylic acid

1361053-47-5

HO-Pro-Oxazole-Thiazole-Pro-Leu-NHBoc

1588428-18-5

2-((S)-1-((R)-2-((S)-1-(2-(2-((S)-1-((tert-butoxycarbonyl)-L-leucyl)pyrrolidin-2-yl)thiazol-4-yl)oxazole-4-carbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)ethyl)thiazole-4-carboxylic acid

1588428-17-4

ethyl 2-((S)-1-((R)-2-amino-3-phenylpropanamido)ethyl)thiazole-4-carboxylate

1588428-18-5

2-((S)-1-((R)-2-((S)-1-(2-(2-((S)-1-((tert-butoxycarbonyl)-L-leucyl)pyrrolidin-2-yl)thiazol-4-yl)oxazole-4-carbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)ethyl)thiazole-4-carboxylic acid

上游原料

ethyl 2-<(S)-1-(N-t-butoxycarbonyl)aminoethyl>thiazole-4-carboxylate ethyl 2-((S)-1-((R)-2-amino-3-phenylpropanamido)ethyl)thiazole-4-carboxylate HO-Pro-Oxazole-Thiazole-Pro-Leu-NHBoc methyl (2-(2-((S)-1-((tert-butoxycarbonyl)-L-leucyl)pyrrolidin-2-yl)thiazol-4-yl)oxazole-4-carbonyl)-L-prolinate

下游产品

(12S,22Z,32Z,52S,122Z,8R,11S,15S)-8-benzyl-15-isobutyl-11-methyl-7,10,14-triaza-3(2,4)-oxazola-2,12(2,4)-dithiazola-1(2,1),5(1,2)-dipyrrolidinacyclohexadecaphane-4,6,9,13,16-pentaone