百科

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

CAS号：1597437-31-4

英文名：tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

分子式：C30H55NO4Si2

分子量：549.933

合成路线

ethyl (S)-2-amino-4-methyl-3-oxopentanoate hydrochloride

ethyl (S)-2-amino-4-methyl-3-oxopentanoate hydrochloride

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

ethyl (2R,3R)-2-((tert-butoxycarbonyl)amino)-3-((tert-butyldimethylsilyl)oxy)-4-methylpentanoate

ethyl (2R,3R)-2-((tert-butoxycarbonyl)amino)-3-((tert-butyldimethylsilyl)oxy)-4-methylpentanoate

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

tert-butyl ((2R,3R)-3-((tert-butyldimethylsilyl)oxy)-4-methyl-1-oxopentan-2-yl)carbamate

tert-butyl ((2R,3R)-3-((tert-butyldimethylsilyl)oxy)-4-methyl-1-oxopentan-2-yl)carbamate

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

(2R,3R)-β-OH-Leu-OEt

(2R,3R)-β-OH-Leu-OEt

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

tert-butyl ((3R,4S,5R,6R,E)-3-((tert-butyldimethylsilyl)oxy)-8-(dimethyl(phenyl)silyl)-5-hydroxy-2,6-dimethylnon-7-en-4-yl)carbamate

上游原料

tert-butyl ((2R,3R)-3-((tert-butyldimethylsilyl)oxy)-4-methyl-1-oxopentan-2-yl)carbamate ethyl (2R,3R)-2-((tert-butoxycarbonyl)amino)-3-((tert-butyldimethylsilyl)oxy)-4-methylpentanoate (2R,3R)-β-OH-Leu-OEt

下游产品

(6S,7S,E)-7-((tert-butyldimethylsilyl)oxy)-N-((5R,6R,7R)-5-((R,E)-4-iodopent-3-en-2-yl)-7-isopropyl-2,2,3,3,9,9,10,10-octamethyl-4,8-dioxa-3,9-disilaundecan-6-yl)-4,4,6,8-tetramethyl-5-oxonon-2-enamide