百科

Trifluoro-acetic acid (3R,9S,11S,13R,14S,16S)-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-benzyl]-16-isopropyl-4,9,11,13-tetramethyl-2,5,8-trioxo-1-oxa-4,7-diaza-cyclohexadec-14-yl ester

CAS号：160531-35-1

英文名：Trifluoro-acetic acid (3R,9S,11S,13R,14S,16S)-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-benzyl]-16-isopropyl-4,9,11,13-tetramethyl-2,5,8-trioxo-1-oxa-4,7-diaza-cyclohexadec-14-yl ester

分子式：C35H54F3IN2O7Si

分子量：826.798

合成路线

1028272-13-0

(2S,3R,4R,5R,7S)-7-Benzyloxy-3-hydroxy-5-methoxymethoxy-2,4,8-trimethyl-nonanoic acid

160531-35-1

Trifluoro-acetic acid (3R,9S,11S,13R,14S,16S)-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-benzyl]-16-isopropyl-4,9,11,13-tetramethyl-2,5,8-trioxo-1-oxa-4,7-diaza-cyclohexadec-14-yl ester

1025824-33-2

(2S,3R,4S,6R,7R,9S)-9-Benzyloxy-3-hydroxy-7-methoxymethoxy-2,4,6,10-tetramethyl-undecanoic acid

160531-35-1

Trifluoro-acetic acid (3R,9S,11S,13R,14S,16S)-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-benzyl]-16-isopropyl-4,9,11,13-tetramethyl-2,5,8-trioxo-1-oxa-4,7-diaza-cyclohexadec-14-yl ester

160531-47-5

N-Boc-3-iodo-N-methyl-D-tyrosine methyl ester

160531-35-1

Trifluoro-acetic acid (3R,9S,11S,13R,14S,16S)-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-benzyl]-16-isopropyl-4,9,11,13-tetramethyl-2,5,8-trioxo-1-oxa-4,7-diaza-cyclohexadec-14-yl ester

160531-48-6

(R)-2-(tert-Butoxycarbonyl-methyl-amino)-3-(4-tert-butoxycarbonyloxy-3-iodo-phenyl)-propionic acid methyl ester

160531-35-1

Trifluoro-acetic acid (3R,9S,11S,13R,14S,16S)-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-benzyl]-16-isopropyl-4,9,11,13-tetramethyl-2,5,8-trioxo-1-oxa-4,7-diaza-cyclohexadec-14-yl ester

上游原料

N-Boc-3-iodo-N-methyl-D-tyrosine methyl ester (2S,3R,4S,6R,7R,9S)-9-Benzyloxy-3-hydroxy-7-methoxymethoxy-2,4,6,10-tetramethyl-undecanoic acid (R)-2-(tert-Butoxycarbonyl-methyl-amino)-3-(4-tert-butoxycarbonyloxy-3-iodo-phenyl)-propionic acid methyl ester (2S,3R,4R,5R,7S)-7-Benzyloxy-3-hydroxy-5-methoxymethoxy-2,4,8-trimethyl-nonanoic acid

下游产品

deoxydoliculide silyl ether Imidazole-1-carbothioic acid O-{(3R,9S,11S,13R,14S,16S)-3-[4-(tert-butyl-dimethyl-silanyloxy)-benzyl]-16-isopropyl-4,9,11,13-tetramethyl-2,5,8-trioxo-1-oxa-4,7-diaza-cyclohexadec-14-yl} ester deiododoliculide silyl ether