百科

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

CAS号：1620955-91-0

英文名：tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

分子式：C39H40N6O7

分子量：704.771

合成路线

tert-butyl 2-(2-(4-bromophenyl)-1,6-naphthyridine-4-carbonyl)hydrazine-1-carboxylate

tert-butyl 2-(2-(4-bromophenyl)-1,6-naphthyridine-4-carbonyl)hydrazine-1-carboxylate

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

2-(4-bromophenyl)-1,6-naphthyridine-4-carboxylic acid

2-(4-bromophenyl)-1,6-naphthyridine-4-carboxylic acid

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

methyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)isoxazole-5-carboxylate

methyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)isoxazole-5-carboxylate

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

N-[(4-bromophenyl)methylidene]hydroxylamine

N-[(4-bromophenyl)methylidene]hydroxylamine

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

tert-butyl (3-(4'-(4-(2-(tert-butoxycarbonyl)hydrazine-1-carbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)-D-prolinate

上游原料

methyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)isoxazole-5-carboxylate N-[(4-bromophenyl)methylidene]hydroxylamine tert-butyl 2-(2-(4-bromophenyl)-1,6-naphthyridine-4-carbonyl)hydrazine-1-carboxylate 2-(4-bromophenyl)-1,6-naphthyridine-4-carboxylic acid

下游产品

(R)-1-(3-(4'-(4-(hydrazinecarbonyl)-1,6-naphthyridin-2-yl)-[1,1'-biphenyl]-4-yl)isoxazole-5-carbonyl)pyrrolidine-2-carboxylic acid hydrochloride