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2'-O-(叔-丁基二甲基硅烷基)紫杉醇7-O-三氟甲烷磺酸酯

2'-O-(叔-丁基二甲基硅烷基)紫杉醇7-O-三氟甲烷磺酸酯

CAS号:165065-01-0
英文名:2'-O-(t-butyldimethylsilyl)-7β-O-trifluoromethanesulfonyl-paclitaxel
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化合物简介
2'-O-(tert-Butyldimethylsilyl)paclitaxel 7-O-triflate is an intermediate in the synthesis of 6α-Hydroxy Paclitaxel, the major human metabolite of Paclitaxel, an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
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