百科

{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

CAS号：165727-47-9

英文名：{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

分子式：C40H57N3O8Si

分子量：735.981

合成路线

((S)-1-(S)-Oxiranyl-3-phenyl-propyl)-carbamic acid benzyl ester

((S)-1-(S)-Oxiranyl-3-phenyl-propyl)-carbamic acid benzyl ester

{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

((1S,2S)-3-Chloro-2-hydroxy-1-phenethyl-propyl)-carbamic acid benzyl ester

((1S,2S)-3-Chloro-2-hydroxy-1-phenethyl-propyl)-carbamic acid benzyl ester

{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

((S)-3-Chloro-2-oxo-1-phenethyl-propyl)-carbamic acid benzyl ester

((S)-3-Chloro-2-oxo-1-phenethyl-propyl)-carbamic acid benzyl ester

{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

{(1S,2R)-1-Benzyl-3-[((2R,3S)-3-benzyloxycarbonylamino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-2-hydroxy-propyl}-carbamic acid tert-butyl ester

上游原料

((S)-3-Chloro-2-oxo-1-phenethyl-propyl)-carbamic acid benzyl ester ((S)-1-(S)-Oxiranyl-3-phenyl-propyl)-carbamic acid benzyl ester ((1S,2S)-3-Chloro-2-hydroxy-1-phenethyl-propyl)-carbamic acid benzyl ester

下游产品

{(1S,2R)-3-[((2R,3S)-3-Amino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid tert-butyl ester