百科

(13R,14R)-4-benzyloxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.13,7]eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one

(13R,14R)-4-benzyloxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.13,7]eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one

CAS号：172919-05-0

英文名：(13R,14R)-4-benzyloxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.13,7]eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one

分子式：C25H24O6

分子量：420.454

合成路线

ethyl 3-(3'-hydroxy-4'-benzyloxyphenyl)-2E-propenoate

ethyl 3-(3'-hydroxy-4'-benzyloxyphenyl)-2E-propenoate

(13R,14R)-4-benzyloxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.13,7]eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one

(13R,14R)-4-benzyloxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.13,7]eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one

2,2-Dimethyl-propionic acid (2R,3R)-3-{4-[2-benzyloxy-5-(2-carboxy-ethyl)-phenoxy]-phenyl}-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-propyl ester

2,2-Dimethyl-propionic acid (2R,3R)-3-{4-[2-benzyloxy-5-(2-carboxy-ethyl)-phenoxy]-phenyl}-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-propyl ester

(13R,14R)-4-benzyloxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.13,7]eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one

(13R,14R)-4-benzyloxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.13,7]eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one

上游原料

ethyl 3-(3'-hydroxy-4'-benzyloxyphenyl)-2E-propenoate 2,2-Dimethyl-propionic acid (2R,3R)-3-{4-[2-benzyloxy-5-(2-carboxy-ethyl)-phenoxy]-phenyl}-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-propyl ester

下游产品

(13R,14R)-4-hydroxy-13,14-dihydroxy-2,11-dioxatricyclo[13.2.2.13,7]eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one (12S,13R)-46-(benzyloxy)-3,8-dioxa-1(2,3)-oxirana-2(1,4),4(1,3)-dibenzenacyclononaphan-7-one combretastatin D-2 benzyl ether combretastatin D-1 benzyl ether