百科

ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

CAS号：179624-26-1

英文名：ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

分子式：C33H33Cl2N5O5

分子量：650.552

合成路线

N-[2,4-dichloro-3-({[4-(dimethylaamino)-2-methyl-8-quinolinyl]oxy}methyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-methylacetamide

N-[2,4-dichloro-3-({[4-(dimethylaamino)-2-methyl-8-quinolinyl]oxy}methyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-methylacetamide

ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

N-(2,4-Dichloro-3-hydroxymethyl-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-N-methyl-acetamide

N-(2,4-Dichloro-3-hydroxymethyl-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-N-methyl-acetamide

ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

2,6-dichloro-1-methylsulfonyloxymethyl-3-[N-methyl-N-(phthalimidoacetyl)amino]benzene

2,6-dichloro-1-methylsulfonyloxymethyl-3-[N-methyl-N-(phthalimidoacetyl)amino]benzene

ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

ethyl 5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-2-pyridinecarboxylate

上游原料

N-[2,4-dichloro-3-({[4-(dimethylaamino)-2-methyl-8-quinolinyl]oxy}methyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-methylacetamide 2,6-dichloro-1-methylsulfonyloxymethyl-3-[N-methyl-N-(phthalimidoacetyl)amino]benzene N-(2,4-Dichloro-3-hydroxymethyl-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-N-methyl-acetamide

下游产品

5-[(1E)-3-({2-[2,4-dichloro-3-({[4-(dimethylamino)-2-methyl-8-quinolinyl]oxy}methyl)methylanilino]-2-oxoethyl}amino)-3-oxo-1-propenyl]-N-methyl-2-pyridinecarboxamide