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cryptophycin 53

cryptophycin 53

CAS号：186256-68-8

英文名：cryptophycin 53

分子式：C36H45ClN2O8

分子量：669.204

合成路线

(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionic acid tert-butyl ester

(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionic acid tert-butyl ester

cryptophycin 53

cryptophycin 53

ethyl (3S,4R)-3-acetoxy-4-methyl-6-phenylhexan-(5E)-oate

ethyl (3S,4R)-3-acetoxy-4-methyl-6-phenylhexan-(5E)-oate

cryptophycin 53

cryptophycin 53

(R)-tert-butyl 2-amino-3-(4-methoxyphenyl)propionate

(R)-tert-butyl 2-amino-3-(4-methoxyphenyl)propionate

cryptophycin 53

cryptophycin 53

上游原料

ethyl (3S,4R)-3-acetoxy-4-methyl-6-phenylhexan-(5E)-oate (R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionic acid tert-butyl ester (R)-tert-butyl 2-amino-3-(4-methoxyphenyl)propionate

下游产品

cyclo[2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-methylpentanoyl-(2E,5S,6S)-5-hydroxy-6-[(2S,3S)-3-[4-[[[tris(1-methylethyl)silyl]oxy]methyl]phenyl]oxiranyl]-2-heptenoyl-3-chloro-O-methyl-D-tyrosyl] cyclo[2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-methylpentanoyl-(2E,5S,6S)-6-[(2R,3R)-3-(3,4-dimethylphenyl)oxiranyl]-5-hydroxy-2-heptenoyl-3-chloro-O-methyl-D-tyrosyl] cyclo[2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-methylpentanoyl-(2E,5S,6S)-6-[(2R,3R)-3-[4-[(diethylamino)methyl]phenyl]oxiranyl]-5-hydroxy-2-heptenoyl-3-chloro-O-methyl-D-tyrosyl]