合成路线
1-[(2R,3R,3aR,7aR)-3-(tert-Butyl-dimethyl-silanyloxy)-3a-hydroxy-5-oxo-hexahydro-furo[2,3-c]pyran-2-yl]-1H-pyrimidine-2,4-dione
CAS号：186839-96-3
英文名：1-[(2R,3R,3aR,7aR)-3-(tert-Butyl-dimethyl-silanyloxy)-3a-hydroxy-5-oxo-hexahydro-furo[2,3-c]pyran-2-yl]-1H-pyrimidine-2,4-dione
分子式：C17H26N2O7Si
分子量：398.483
上游原料
3-[(benzyloxy)methyl]-1-(β-D-ribofuranosyl)uracil
Bromo-acetic acid (2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-oxo-tetrahydro-furan-2-ylmethyl ester
3-Benzyloxymethyl-1-[(2R,3S,5R)-3-(tert-butyl-dimethyl-silanyloxy)-5-hydroxymethyl-4-oxo-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione
3-Benzyloxymethyl-1-[(2R,3S,5R)-3-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-oxo-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione
3-Benzyloxymethyl-1-[(2R,3R,3aR,7aR)-3-(tert-butyl-dimethyl-silanyloxy)-3a-hydroxy-5-oxo-hexahydro-furo[2,3-c]pyran-2-yl]-1H-pyrimidine-2,4-dione
3-Benzyloxymethyl-1-[(2R,3R,4R,5R)-3-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione
下游产品
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(N-benzylcarbamoylmethyl)-β-D-ribo-pentofuranosyl]cytosine
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(carbamoylmethyl)-β-D-ribo-pentofuranosyl]cytosine
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(carbamoylmethyl)-β-D-ribo-pentofuranosyl]-4-N-methylcytosine
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(N-methylcarbamoylmethyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(N-ethylcarbamoylmethyl)-β-D-ribo-pentofuranosyl]cytosine
[(2R,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-3-yl]-acetonitrile
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonylmethyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(N,N'-dimethylcarbamoylmethyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(N-ethylcarbamoylmethyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(cyanomethyl)-β-D-ribo-pentofuranosyl]cytosine
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(2-phenylselenylethyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(N-benzylcarbamoylmethyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(methoxycarbonyl)-β-D-ribo-pentofuranosyl]cytosine
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(N,N'-dimethylcarbamoylmethyl)-β-D-ribo-pentofuranosyl]cytosine
2-[(2R,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-3-yl]-acetamide
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(carbamoylmethyl)-β-D-ribo-pentofuranosyl]-4-N,N'-dimethylcytosine
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(N-methylcarbamoylmethyl)-β-D-ribo-pentofuranosyl]cytosine
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(2-mesyloxyethyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-ethenyl-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(trans-ethoxycarbonylethenyl)-β-D-ribo-pentofuranosyl]uracil
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(ethoxycarbonylethenyl)-β-D-ribo-pentofuranosyl]cytosine
1-[2,5-di-O-(tert-butyldimethylsilyl)-3-C-(ethoxycarbonylethyl)-β-D-ribo-pentofuranosyl]cytosine
(2R,3R,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-3-carbaldehyde
