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(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

CAS号：187100-37-4

英文名：(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

分子式：C25H53NO3Si

分子量：443.779

合成路线

(2R,3S)-3-methyl-1,2-epoxypentane

(2R,3S)-3-methyl-1,2-epoxypentane

(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

tert-Butyl (4S)-4-<(1'R,13'R,14'S)-13'-tert-butyldimethylsilyloxy-1'-hydroxy-14'-methylhexadec-2'-ynyl>-2,2-dimethyloxazolidine-3-carboxylate

tert-Butyl (4S)-4-<(1'R,13'R,14'S)-13'-tert-butyldimethylsilyloxy-1'-hydroxy-14'-methylhexadec-2'-ynyl>-2,2-dimethyloxazolidine-3-carboxylate

(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

(12R,13S)-13-Methylpentadec-1-yn-12-ol

(12R,13S)-13-Methylpentadec-1-yn-12-ol

(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

(E)-(2S,3R,15R,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol

上游原料

tert-Butyl (4S)-4-<(1'R,13'R,14'S)-13'-tert-butyldimethylsilyloxy-1'-hydroxy-14'-methylhexadec-2'-ynyl>-2,2-dimethyloxazolidine-3-carboxylate (12R,13S)-13-Methylpentadec-1-yn-12-ol (2R,3S)-3-methyl-1,2-epoxypentane

下游产品

(2S,3S,4R,15R,16S)-1,3,15-Tris-tert-butyldimethylsilyloxy-16-methyl-2-p-tolylsulfonylaminooctadecan-4-yl mesylate