化合物简介
3,4,5,6-Tetrahydrouridine, is a derivative of Uridine. Tetrahydrouridine (THU), is a potent inhibitor of cytidine. It inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels deaminase (CDA), and thus can be used as a potential and promising treatment for tumors with highly expressed CDA.
基本信息
中文名称
四氢尿苷
英文名称
TETRAHYDROURIDINE
中文别名
英文别名
3,4,5,6-tetrahydrouridine、Tetrahydro-uridin
CAS号
18771-50-1
分子式
C9H16N2O6
分子量
248.233
精确质量
248.101
PSA
130.33
LOGP
-2.73
编号系统
UNII
0NIZ8H6OL8
物化性质
密度
1.622g/cm3
沸点
668.6ºC at 760mmHg
闪点
358.2ºC
折射率
1.654
储存条件
-20ºC
蒸汽压
0.65mmHg at 25°C
合成路线