化合物简介
Pipamperone (INN, USAN, BAN), also known as carpiperone and floropipamide or fluoropipamide, and as floropipamide hydrochloride (JAN), is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It is or has been marketed under brand names including Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. Pipamperone was discovered at Janssen Pharmaceutica in 1961, and entered clinical trials in the United States in 1963.
基本信息
中文名称
酰胺哌啶酮
英文名称
pipamperone
中文别名
氟丙哌隆
英文别名
Dipiperal、piperonil、floropipamide、MCN-JR-3345、Dipiperon、Pipamperone、R 3345、Piperonyl、Propitan、Floropipamid、PIPAMPERONE DIHYDROCHLORIDE APPROX. 99、1\'-[4-(4-fluoro-phenyl)-4-oxo-butyl]-octahydro-[1,4\']bipyridinyl-4\'-carboxylic acid amide、FPA、Dipiperone、1\'-[3-(p-fluorobenzoyl)propyl]-[1,4\'-bipiperidine]-4\'-carboxamide
CAS号
1893-33-0
分子式
C21H30FN3O2
分子量
375.48
精确质量
375.232
PSA
66.64
LOGP
3.1705
编号系统
UNII
5402501F0W
物化性质
密度
1.174g/cm3
沸点
563.7ºC at 760 mmHg
闪点
294.7ºC
折射率
1.556
蒸汽压
9.88E-13mmHg at 25°C
安全信息
危险类别码
R22
WGK Germany
1
海关编码
2933399090
危险品标志
Xn