百科

(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

CAS号：191155-23-4

英文名：(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

分子式：C24H22N6O3

分子量：442.47

合成路线

(2S,3aS,8aR)-3a-Allyl-2-((R)-1-methoxycarbonyl-ethylcarbamoyl)-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,8-dicarboxylic acid di-tert-butyl ester

(2S,3aS,8aR)-3a-Allyl-2-((R)-1-methoxycarbonyl-ethylcarbamoyl)-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,8-dicarboxylic acid di-tert-butyl ester

(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

tert-butyl (+)-(S)-3-[2-(tert-butoxycarbonylamino)-3-methoxy-3-oxopropyl]-1H-indole-1-carboxylate

tert-butyl (+)-(S)-3-[2-(tert-butoxycarbonylamino)-3-methoxy-3-oxopropyl]-1H-indole-1-carboxylate

(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

(2S,3aS,8aR)-3a-Allyl-2-fluorocarbonyl-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,8-dicarboxylic acid di-tert-butyl ester

(2S,3aS,8aR)-3a-Allyl-2-fluorocarbonyl-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,8-dicarboxylic acid di-tert-butyl ester

(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

(3R,5aS,10bS,11aS)-10b-Allyl-2-(2-azido-benzoyl)-3-methyl-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

上游原料

(2S,3aS,8aR)-3a-Allyl-2-fluorocarbonyl-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,8-dicarboxylic acid di-tert-butyl ester (2S,3aS,8aR)-3a-Allyl-2-((R)-1-methoxycarbonyl-ethylcarbamoyl)-2,3,3a,8a-tetrahydro-pyrrolo[2,3-b]indole-1,8-dicarboxylic acid di-tert-butyl ester tert-butyl (+)-(S)-3-[2-(tert-butoxycarbonylamino)-3-methoxy-3-oxopropyl]-1H-indole-1-carboxylate

下游产品

(7R,9aS,14bS,15aS)-14b-allyl-7-methyl-10,14b,15,15a-tetrahydroindolo[3'',2'':4',5']pyrrolo[2',1':3,4]pyrazino[2,1-b]quinazoline-5,8(7H,9aH)-dione