百科

(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

CAS号：191163-56-1

英文名：(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

分子式：C27H28N2O5

分子量：460.522

合成路线

1,2-O-isopropylidene-3-C-(prop-1-en-3-yl)-α-D-ribofuranose

1,2-O-isopropylidene-3-C-(prop-1-en-3-yl)-α-D-ribofuranose

(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

1,2-O-isopropylidene-3-C-(prop-1-en-3-yl)-3,5-di-O-benzyl-α-D-ribofuranose

1,2-O-isopropylidene-3-C-(prop-1-en-3-yl)-3,5-di-O-benzyl-α-D-ribofuranose

(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

3-C-Allyl-1,2-di-O-acetyl-3,5-di-O-benzyl-D-ribofuranose

3-C-Allyl-1,2-di-O-acetyl-3,5-di-O-benzyl-D-ribofuranose

(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

(2R,3R,3aS,9aR)-3-Allyl-3-benzyloxy-2-benzyloxymethyl-7-methyl-2,3,3a,9a-tetrahydro-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one

上游原料

3-C-Allyl-1,2-di-O-acetyl-3,5-di-O-benzyl-D-ribofuranose 1,2-O-isopropylidene-3-C-(prop-1-en-3-yl)-α-D-ribofuranose 1,2-O-isopropylidene-3-C-(prop-1-en-3-yl)-3,5-di-O-benzyl-α-D-ribofuranose

下游产品

(1S,5R,6R,8R)-5-Hydroxy-6-hydroxymethyl-8-(thymin-1-yl)-2,7-dioxabicyclo[3.3.0]octane (1S,5R,6R,8R)-5-Benzyloxy-6-benzyloxymethyl-8-(thymin-1-yl)-2,7-dioxabicyclo[3.3.0]octane 1-[3,5-Di-O-benzyl-3-C-(3-hydroxypropyl)-β-D-arabinofuranosyl]thymine 1-[3,5-Di-O-benzyl-3-C-(2-hydroxyethyl)-β-D-arabinofuranosyl]thymine (1S,6R,7R,9R)-6-Benzyloxy-7-benzyloxymethyl-9-(thymin-1-yl)-2,8-dioxabicyclo[4.3.0]nonane