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(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

CAS号：194414-56-7

英文名：(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

分子式：C24H31N3O7

分子量：473.519

合成路线

(R)-2-Methoxycarbonylmethyl-2-methyl-1-thiosuccinimide

(R)-2-Methoxycarbonylmethyl-2-methyl-1-thiosuccinimide

{[5-tert-Butoxycarbonyl-4-(2-methoxycarbonyl-ethyl)-3-methyl-1H-pyrrol-2-yl]-cyano-methyl}-triphenyl-phosphonium

{[5-tert-Butoxycarbonyl-4-(2-methoxycarbonyl-ethyl)-3-methyl-1H-pyrrol-2-yl]-cyano-methyl}-triphenyl-phosphonium

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

methyl 5-methyl-4,6-dioxoheptanoate

methyl 5-methyl-4,6-dioxoheptanoate

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

5-acetoxymethyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-pyrrole-2-carboxylic acid tert-butyl ester

5-acetoxymethyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-pyrrole-2-carboxylic acid tert-butyl ester

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

tert-Butyl 3-(2-methoxycarbonylethyl)-4,5-dimethylpyrrole-2-carboxylate

tert-Butyl 3-(2-methoxycarbonylethyl)-4,5-dimethylpyrrole-2-carboxylate

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

(S)-2-Methoxycarbonylmethyl-2-methyldithiosuccinimide

(S)-2-Methoxycarbonylmethyl-2-methyldithiosuccinimide

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

5-Cyanomethyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester

5-Cyanomethyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

(3R,4E)-9-tert-Butoxycarbonyl-5-cyano-8-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3,7-dimethyl-2,3-dihydrodipyrrin-1(10H)-one

上游原料

(S)-2-Methoxycarbonylmethyl-2-methyldithiosuccinimide 5-acetoxymethyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-pyrrole-2-carboxylic acid tert-butyl ester methyl 5-methyl-4,6-dioxoheptanoate {[5-tert-Butoxycarbonyl-4-(2-methoxycarbonyl-ethyl)-3-methyl-1H-pyrrol-2-yl]-cyano-methyl}-triphenyl-phosphonium tert-Butyl 3-(2-methoxycarbonylethyl)-4,5-dimethylpyrrole-2-carboxylate (R)-2-Methoxycarbonylmethyl-2-methyl-1-thiosuccinimide 5-Cyanomethyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester

下游产品

5-{2-Amino-1-[(R)-3-methoxycarbonylmethyl-3-methyl-5-oxo-pyrrolidin-(2Z)-ylidene]-ethyl}-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester