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(3S,4R)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-[(1R,4R)-4-(2-methoxy-ethyl)-2-oxo-cyclohexyl]-azetidin-2-one

(3S,4R)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-[(1R,4R)-4-(2-methoxy-ethyl)-2-oxo-cyclohexyl]-azetidin-2-one

CAS号：194535-49-4

英文名：(3S,4R)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-[(1R,4R)-4-(2-methoxy-ethyl)-2-oxo-cyclohexyl]-azetidin-2-one

分子式：C26H51NO4Si2

分子量：497.858

合成路线

allyl 2-oxocyclohex-3-ene-1-carboxylate

allyl 2-oxocyclohex-3-ene-1-carboxylate

(3S,4R)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-[(1R,4R)-4-(2-methoxy-ethyl)-2-oxo-cyclohexyl]-azetidin-2-one

(3S,4R)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-[(1R,4R)-4-(2-methoxy-ethyl)-2-oxo-cyclohexyl]-azetidin-2-one

((1R,4R)-4-{(2R,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-3-oxo-cyclohexyl)-acetaldehyde

((1R,4R)-4-{(2R,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-3-oxo-cyclohexyl)-acetaldehyde

(3S,4R)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-[(1R,4R)-4-(2-methoxy-ethyl)-2-oxo-cyclohexyl]-azetidin-2-one

(3S,4R)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-[(1R,4R)-4-(2-methoxy-ethyl)-2-oxo-cyclohexyl]-azetidin-2-one

上游原料

allyl 2-oxocyclohex-3-ene-1-carboxylate ((1R,4R)-4-{(2R,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-3-oxo-cyclohexyl)-acetaldehyde

下游产品

(1S,6S,8aS,8bR)-1-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-6-(2-methoxy-ethyl)-2-oxo-1,2,5,6,7,8,8a,8b-octahydro-azeto[2,1-a]isoindole-4-carboxylic acid benzyl ester {(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,4R)-4-(2-methoxy-ethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid benzyl ester