百科

(2R,3S,5R)-3-Benzoyloxy-2-benzoyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carboxylic acid

(2R,3S,5R)-3-Benzoyloxy-2-benzoyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carboxylic acid

CAS号：194652-86-3

英文名：(2R,3S,5R)-3-Benzoyloxy-2-benzoyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carboxylic acid

分子式：C25H22N2O9

分子量：494.45

合成路线

1-(3-O-Benzoyl-4-C-benzoyloxymethyl-2-deoxy-α-L-threo-pentofuranosyl)thymine

1-(3-O-Benzoyl-4-C-benzoyloxymethyl-2-deoxy-α-L-threo-pentofuranosyl)thymine

(2R,3S,5R)-3-Benzoyloxy-2-benzoyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carboxylic acid

(2R,3S,5R)-3-Benzoyloxy-2-benzoyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carboxylic acid

1-((2R,4S,5S)-4-Hydroxy-5-hydroxymethyl-5-trityloxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

1-((2R,4S,5S)-4-Hydroxy-5-hydroxymethyl-5-trityloxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione

(2R,3S,5R)-3-Benzoyloxy-2-benzoyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carboxylic acid

(2R,3S,5R)-3-Benzoyloxy-2-benzoyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carboxylic acid

上游原料

1-((2R,4S,5S)-4-Hydroxy-5-hydroxymethyl-5-trityloxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione 1-(3-O-Benzoyl-4-C-benzoyloxymethyl-2-deoxy-α-L-threo-pentofuranosyl)thymine

下游产品

N-[(Aminocarbonyl)methyl]-3',5'-di-O-benzoylthymidine-4'-carboxamide 4'-methoxycarbonylthymidine N-(2-Hydroxymethyl)-3',5'-di-O-benzoylthymidine-4'-carboxamide Thymidine-4'-C-carboxylic acid N,N-Dimethyl-3',5'-di-O-benzoylthymidine-4'-carboxamide