百科

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

CAS号：196868-11-8

英文名：2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

分子式：C18H24N4O5

分子量：376.407

合成路线

3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose

3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

1,2-O-isopropylidene-5-O-(tert-butyl)dimethylsilyl-α-D-ribofuranoside

1,2-O-isopropylidene-5-O-(tert-butyl)dimethylsilyl-α-D-ribofuranoside

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

Trifluoro-methanesulfonic acid (3aR,5R,6R,6aR)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

Trifluoro-methanesulfonic acid (3aR,5R,6R,6aR)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

((3aR,5S,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-tert-butyl-dimethyl-silane

((3aR,5S,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-tert-butyl-dimethyl-silane

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

2-[((3aR,5R,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-amino]-3-phenyl-propionic acid methyl ester

上游原料

3-azido-3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose Trifluoro-methanesulfonic acid (3aR,5R,6R,6aR)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester ((3aR,5S,6S,6aR)-6-Azido-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-tert-butyl-dimethyl-silane 1,2-O-isopropylidene-5-O-(tert-butyl)dimethylsilyl-α-D-ribofuranoside

下游产品

2-((3R,4R,5S)-4-Acetylamino-3,5-dihydroxy-piperidin-1-yl)-3-phenyl-propionic acid methyl ester 2-[((3aR,5R,6S,6aR)-6-Acetylamino-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl)-benzyloxycarbonyl-amino]-3-phenyl-propionic acid methyl ester