百科

1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

CAS号：200119-09-1

英文名：1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

分子式：C22H42N2O6Si2

分子量：486.75

合成路线

甲基-2-脱氧-beta-L-赤式戊呋喃糖

甲基-2-脱氧-beta-L-赤式戊呋喃糖

1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

1-[(4S,5R)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

1-[(4S,5R)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

(2R,3S,5S)-3-Allyl-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-methoxy-tetrahydro-furan-3-ol

(2R,3S,5S)-3-Allyl-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-methoxy-tetrahydro-furan-3-ol

1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

1-[(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(3-hydroxy-propyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

上游原料

甲基-2-脱氧-beta-L-赤式戊呋喃糖 1-[(4S,5R)-4-Allyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-trimethylsilanyloxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione (2R,3S,5S)-3-Allyl-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-methoxy-tetrahydro-furan-3-ol

下游产品

5'-O-(4,4'-dimethoxytrityl)-3'-C-[3-(phthalimido)propyl]thymidine 2-{3-[(2R,3S,5S)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-propyl}-isoindole-1,3-dione 2-{3-[(2R,3S)-3-Hydroxy-2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-propyl}-isoindole-1,3-dione