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(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

CAS号：204379-33-9

英文名：(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

分子式：C13H15ClN4O3

分子量：310.736

合成路线

(1S,4R)-4-(5-amino-6-chloropyrimidin-4-yl)cyclopent-2-enyl acetate

(1S,4R)-4-(5-amino-6-chloropyrimidin-4-yl)cyclopent-2-enyl acetate

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

9-[(3aS,4R,6S,6aS)-6-(tert-Butyl-dimethyl-silanyloxy)-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl]-6-chloro-9H-purine

9-[(3aS,4R,6S,6aS)-6-(tert-Butyl-dimethyl-silanyloxy)-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl]-6-chloro-9H-purine

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

acetic acid 4-(6-chloropurin-9-yl)-2,3-dihydroxy-cyclopentyl ester

acetic acid 4-(6-chloropurin-9-yl)-2,3-dihydroxy-cyclopentyl ester

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

(1S,2S,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(6-chloro-purin-9-yl)-cyclopentane-1,2-diol

(1S,2S,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(6-chloro-purin-9-yl)-cyclopentane-1,2-diol

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

(3aR,5R,6R,6aS)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol

上游原料

9-[(3aS,4R,6S,6aS)-6-(tert-Butyl-dimethyl-silanyloxy)-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl]-6-chloro-9H-purine (1S,4R)-4-(5-amino-6-chloropyrimidin-4-yl)cyclopent-2-enyl acetate (1S,2S,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(6-chloro-purin-9-yl)-cyclopentane-1,2-diol acetic acid 4-(6-chloropurin-9-yl)-2,3-dihydroxy-cyclopentyl ester

下游产品

(2S,3S,4R)-4-(6-chloro-9H-purin-9-yl)-2,3-(isopropylidenedioxy)cyclopent-1-one (1S,2S,5R)-5-(6-chloro-9H-purin-9-yl)-3,3-difluoro-1,2-(isopropylidenedioxy)cyclopentane (2S,3S,5R)-4-(6-amino-9H-purin-9-yl)-3,3-difluoro-1,2-(isopropylidenedioxy)cyclopentane