百科

(4R,4aS,6S,7aS)-6-Methyl-4-(2,2,6,6-tetramethyl-piperidin-1-yloxymethyl)-2-trichloromethyl-4a,6,7,7a-tetrahydro-4H-furo[2,3-e][1,3]oxazine

(4R,4aS,6S,7aS)-6-Methyl-4-(2,2,6,6-tetramethyl-piperidin-1-yloxymethyl)-2-trichloromethyl-4a,6,7,7a-tetrahydro-4H-furo[2,3-e][1,3]oxazine

CAS号：207123-33-9

英文名：(4R,4aS,6S,7aS)-6-Methyl-4-(2,2,6,6-tetramethyl-piperidin-1-yloxymethyl)-2-trichloromethyl-4a,6,7,7a-tetrahydro-4H-furo[2,3-e][1,3]oxazine

分子式：C18H29Cl3N2O3

分子量：427.793

合成路线

(S,S)-2,2-dimethyl-4-[(tert-butyldimethylsilyloxy)methyl]-5-vinyl-1,3-dioxolane

(S,S)-2,2-dimethyl-4-[(tert-butyldimethylsilyloxy)methyl]-5-vinyl-1,3-dioxolane

(4R,4aS,6S,7aS)-6-Methyl-4-(2,2,6,6-tetramethyl-piperidin-1-yloxymethyl)-2-trichloromethyl-4a,6,7,7a-tetrahydro-4H-furo[2,3-e][1,3]oxazine

(4R,4aS,6S,7aS)-6-Methyl-4-(2,2,6,6-tetramethyl-piperidin-1-yloxymethyl)-2-trichloromethyl-4a,6,7,7a-tetrahydro-4H-furo[2,3-e][1,3]oxazine

上游原料

(S,S)-2,2-dimethyl-4-[(tert-butyldimethylsilyloxy)methyl]-5-vinyl-1,3-dioxolane

下游产品

[(R)-1-((2R,5S)-5-Methyl-2,5-dihydro-furan-2-yl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl]-carbamic acid benzyl ester [(R)-1-((2S,3S,5S)-3-Hydroxy-5-methyl-tetrahydro-furan-2-yl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl]-carbamic acid benzyl ester (S)-Benzyloxycarbonylamino-((2R,5S)-5-methyl-2,5-dihydro-furan-2-yl)-acetic acid