N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

CAS号：209968-92-3

英文名：N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

分子式：C30H43N5O6Si2

分子量：625.863

合成路线

Toluene-4-sulfonic acid (2R,3R,3aS,9aS)-2-(6-benzoylamino-purin-9-yl)-3-hydroxy-5,5,7,7-tetraisopropyl-dihydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-9a-ylmethyl ester

Toluene-4-sulfonic acid (2R,3R,3aS,9aS)-2-(6-benzoylamino-purin-9-yl)-3-hydroxy-5,5,7,7-tetraisopropyl-dihydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-9a-ylmethyl ester

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

N6-benzoyl-5'-hydroxymethyl-O2',O3'-isopropylidene-adenosine

N6-benzoyl-5'-hydroxymethyl-O2',O3'-isopropylidene-adenosine

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

Toluene-4-sulfonic acid (2S,3S,4R,5R)-5-(6-benzoylamino-purin-9-yl)-3,4-dihydroxy-2-hydroxymethyl-tetrahydro-furan-2-ylmethyl ester

Toluene-4-sulfonic acid (2S,3S,4R,5R)-5-(6-benzoylamino-purin-9-yl)-3,4-dihydroxy-2-hydroxymethyl-tetrahydro-furan-2-ylmethyl ester

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

Toluene-4-sulfonic acid (3aS,4S,6R,6aR)-6-(6-benzoylamino-purin-9-yl)-4-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester

Toluene-4-sulfonic acid (3aS,4S,6R,6aR)-6-(6-benzoylamino-purin-9-yl)-4-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

N-[9-((1R,8S,9R,13R)-4,4,6,6-Tetraisopropyl-3,5,7,10,12-pentaoxa-4,6-disila-tricyclo[7.2.2.01,8]tridec-13-yl)-9H-purin-6-yl]-benzamide

上游原料

N6-benzoyl-5'-hydroxymethyl-O2',O3'-isopropylidene-adenosine Toluene-4-sulfonic acid (2S,3S,4R,5R)-5-(6-benzoylamino-purin-9-yl)-3,4-dihydroxy-2-hydroxymethyl-tetrahydro-furan-2-ylmethyl ester Toluene-4-sulfonic acid (3aS,4S,6R,6aR)-6-(6-benzoylamino-purin-9-yl)-4-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester Toluene-4-sulfonic acid (2R,3R,3aS,9aS)-2-(6-benzoylamino-purin-9-yl)-3-hydroxy-5,5,7,7-tetraisopropyl-dihydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-9a-ylmethyl ester

下游产品

(1S,3R,4R,7S)-3-(6-N-benzoyladenine-9-yl)-7-hydroxy-1-hydroxymethyl-2,5-dioxabicyclo[2.2.1]heptane