百科

2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

CAS号：219663-32-8

英文名：2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

分子式：C13H19Cl3INO4

分子量：486.558

合成路线

(Z)-(S)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-4-ene-1,3-diol

(Z)-(S)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-4-ene-1,3-diol

2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

2,2,2-Trichloro-acetimidic acid (Z)-(S)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-[2-(2,2,2-trichloro-acetimidoyloxy)-ethyl]-but-2-enyl ester

2,2,2-Trichloro-acetimidic acid (Z)-(S)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-[2-(2,2,2-trichloro-acetimidoyloxy)-ethyl]-but-2-enyl ester

2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

2,2,2-Trichloro-acetimidic acid 2-{(4R,5S)-4-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-2-trichloromethyl-4,5-dihydro-oxazol-5-yl}-ethyl ester

2,2,2-Trichloro-acetimidic acid 2-{(4R,5S)-4-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-2-trichloromethyl-4,5-dihydro-oxazol-5-yl}-ethyl ester

2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

2,2,2-Trichloro-1-{(2R,3S)-2-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-3-hydroxy-pyrrolidin-1-yl}-ethanone

上游原料

(Z)-(S)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-4-ene-1,3-diol 2,2,2-Trichloro-acetimidic acid 2-{(4R,5S)-4-[(R)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-iodo-ethyl]-2-trichloromethyl-4,5-dihydro-oxazol-5-yl}-ethyl ester 2,2,2-Trichloro-acetimidic acid (Z)-(S)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-[2-(2,2,2-trichloro-acetimidoyloxy)-ethyl]-but-2-enyl ester

下游产品

(2R,3S)-2-[(1S,3S)-1,3-Dihydroxy-4-(2,4,6-trimethyl-benzenesulfonyloxy)-butyl]-3-hydroxy-pyrrolidine-1-carboxylic acid benzyl ester