百科

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

CAS号：219780-51-5

英文名：(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

分子式：C26H34O6

分子量：442.545

合成路线

(S)-1-Hydroxy-4,6,6-trimethyl-5-[1-phenylsulfanyl-meth-(E)-ylidene]-3-triisopropylsilanyloxy-cyclohex-3-enecarbaldehyde

(S)-1-Hydroxy-4,6,6-trimethyl-5-[1-phenylsulfanyl-meth-(E)-ylidene]-3-triisopropylsilanyloxy-cyclohex-3-enecarbaldehyde

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

(3aS,8R,9R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-6,14,14-trimethyl-8-(phenylthio)-9,11,12,13b-tetrahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilol-5(8H)-one

(3aS,8R,9R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-6,14,14-trimethyl-8-(phenylthio)-9,11,12,13b-tetrahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilol-5(8H)-one

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

(3aS,5S,9S,10S,13R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-5-((tert-butyldimethylsilyl)oxy)-6,14,14-trimethyl-5,8,9,10,11,12,13,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilole-10,13-diol

(3aS,5S,9S,10S,13R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-5-((tert-butyldimethylsilyl)oxy)-6,14,14-trimethyl-5,8,9,10,11,12,13,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilole-10,13-diol

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

(3aS,5S,8R,9R,10S,13R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-5-((tert-butyldimethylsilyl)oxy)-6,16,16-trimethyl-8-(phenylthio)-5,8,9,10,11,12,13,13b-octahydro-4H-10,13-epidioxy-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilole

(3aS,5S,8R,9R,10S,13R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-5-((tert-butyldimethylsilyl)oxy)-6,16,16-trimethyl-8-(phenylthio)-5,8,9,10,11,12,13,13b-octahydro-4H-10,13-epidioxy-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilole

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

(2S,3aS,5S,9S,9aS,10S,13bS)-6,9a,14,14-tetramethyl-2-phenyl-5,8,9,9a,10,11,12,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3]dioxole-5,9,10,13-tetraol

上游原料

(S)-1-Hydroxy-4,6,6-trimethyl-5-[1-phenylsulfanyl-meth-(E)-ylidene]-3-triisopropylsilanyloxy-cyclohex-3-enecarbaldehyde (3aS,5S,8R,9R,10S,13R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-5-((tert-butyldimethylsilyl)oxy)-6,16,16-trimethyl-8-(phenylthio)-5,8,9,10,11,12,13,13b-octahydro-4H-10,13-epidioxy-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilole (3aS,5S,9S,10S,13R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-5-((tert-butyldimethylsilyl)oxy)-6,14,14-trimethyl-5,8,9,10,11,12,13,13b-octahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilole-10,13-diol (3aS,8R,9R,13bS)-9-(benzyloxy)-2,2-di-tert-butyl-6,14,14-trimethyl-8-(phenylthio)-9,11,12,13b-tetrahydro-4H-3a,7-methanobenzo[3,4]cyclodeca[1,2-d][1,3,2]dioxasilol-5(8H)-one

下游产品

7-O-(2,2,2-三氯乙氧基羰基)浆果赤霉素 III 紫杉醇