百科

[(8R,9S,13S,14S,16S,17S)-16-(3-Azido-propyl)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy]-tert-butyl-dimethyl-silane

[(8R,9S,13S,14S,16S,17S)-16-(3-Azido-propyl)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy]-tert-butyl-dimethyl-silane

CAS号：220810-53-7

英文名：[(8R,9S,13S,14S,16S,17S)-16-(3-Azido-propyl)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy]-tert-butyl-dimethyl-silane

分子式：C32H51N3O3Si

分子量：553.851

合成路线

3-[(8R,9S,13S,14S,16S,17S)-3-(tert-Butyl-dimethyl-silanyloxy)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-yl]-propan-1-ol

3-[(8R,9S,13S,14S,16S,17S)-3-(tert-Butyl-dimethyl-silanyloxy)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-yl]-propan-1-ol

[(8R,9S,13S,14S,16S,17S)-16-(3-Azido-propyl)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy]-tert-butyl-dimethyl-silane

[(8R,9S,13S,14S,16S,17S)-16-(3-Azido-propyl)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy]-tert-butyl-dimethyl-silane

tertiary butyldimethylsilyloxy estrone

tertiary butyldimethylsilyloxy estrone

[(8R,9S,13S,14S,16S,17S)-16-(3-Azido-propyl)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy]-tert-butyl-dimethyl-silane

[(8R,9S,13S,14S,16S,17S)-16-(3-Azido-propyl)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy]-tert-butyl-dimethyl-silane

上游原料

tertiary butyldimethylsilyloxy estrone 3-[(8R,9S,13S,14S,16S,17S)-3-(tert-Butyl-dimethyl-silanyloxy)-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-yl]-propan-1-ol

下游产品

N-{3-[3-(t-butyldimethylsilyloxy)-17β-(tetrahydro-2H-pyran-2-yl-oxy)-estra-1,3,5(10)-trien-16β-yl]-propyl}-2-(S)-[4-(t-butoxycarbonylamino)-butyl]-2-(t-butoxycarbonyl-amino)-acetamide N-{3-[3-(t-butyldimethylsilyloxy)-17β-(tetrahydro-2H-pyran-2-yl-oxy)-estra-1,3,5(10)-trien-16β-yl]-propyl}-2-(S)-methyl-2-[Nα-[Nβ-(t-butoxycarbonylamino)-L-alanyl]-L-alanyl]-acetamide