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4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

CAS号：231278-20-9

英文名：N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

分子式：C21H14ClFIN3O

分子量：505.711

合成路线

3-氯-4-(3-氟苄氧基)硝基苯

3-氯-4-(3-氟苄氧基)硝基苯

4-氯-6-碘喹唑啉

4-氯-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

N'-(2-cyano-4-iodo-phenyl)-N,N-dimethyl-formamidine

N'-(2-cyano-4-iodo-phenyl)-N,N-dimethyl-formamidine

3-氯-4-(3-氟苄氧基)苯胺

3-氯-4-(3-氟苄氧基)苯胺

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

2-氯-4-硝基苯酚

2-氯-4-硝基苯酚

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

3-氟溴苄

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

2-氨基苯甲腈

2-氨基苯甲腈

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

6-碘-4(H)-喹唑啉酮

6-碘-4(H)-喹唑啉酮

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

3-氯-4-氟硝基苯

3-氯-4-氟硝基苯

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

3-氟苄醇

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

2-氨基-5-碘苯甲酸

2-氨基-5-碘苯甲酸

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

2-氨基-5-碘苯甲腈

2-氨基-5-碘苯甲腈

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

4-[3-氯-4-(3-氟苄基氧)苯基氨基]-6-碘喹唑啉

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上游原料

3-氟溴苄 3-氯-4-氟硝基苯 2-氨基-5-碘苯甲酸 2-氨基苯甲腈 6-碘-4(H)-喹唑啉酮 2-氯-4-硝基苯酚 4-氯-6-碘喹唑啉 3-氯-4-(3-氟苄氧基)苯胺 N(1)-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-N,N-dimethylformamidine 3-氯-4-(3-氟苄氧基)硝基苯 3-chloro-4-(3-fluoro-benzyloxy)-phenylamine hydrochloride 2-氨基-5-碘苯甲腈 4-(3-Fluoro-benzyloxy)-phenylamine N'-(2-cyano-4-iodo-phenyl)-N,N-dimethyl-formamidine 3-氟苄醇

下游产品

(4-(3-Fluoro-benzyloxy)-3-chlorophenyl)-(6-(2-((2-methanesulphonyl-ethylamino)methyl)-thiazol-4-yl)-quinazolin-4-yl)-amine 5-[4-[3-氯-4-(3-氟苯氧基)苯胺基]-6-喹唑啉基]呋喃-2-甲醛一水合二对甲苯磺酸拉帕替尼拉帕替尼