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2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

CAS号：239080-25-2

英文名：2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

分子式：C54H64BrN7O13Si

分子量：1127.11

合成路线

5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(hydroxymethyl)cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(hydroxymethyl)cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

N-1-(2,4-dinitrophenyl)-5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine

N-1-(2,4-dinitrophenyl)-5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine

5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

2-bromo-5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide

上游原料

5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(hydroxymethyl)cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide 5-[[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]aminomethyleneamino]-1-[5-O-(monomethoxytrityl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-(N-2,4-dinitrophenyl)carboxamide 5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine N-1-(2,4-dinitrophenyl)-5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine

下游产品

8-bromo-N-1-[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(bisphenylthiophosphoryl)oxy]methyl]cyclopentyl]-2',3'-O-isopropylideneinosine 8-bromo-N-1-[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(bisphenylthiophosphoryl)oxy]methyl]cyclopentyl]-5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine 8-bromo-N-1-[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(bisphenylthiophosphoryl)oxy]methyl]cyclopentyl]-5'-O-(dianilinophosphoryl)-2',3'-O-isopropylideneinosine 8-bromo-N-1-[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(dianilinophosphoryl)oxy]methyl]cyclopentyl]-2',3'-O-isopropylideneinosine