百科

(R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester

CAS号：253189-34-3

英文名：(R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester

分子式：C26H40ClIN2O8Si

分子量：699.047

合成路线

253189-14-9

(4S,5R)-2-Iodo-4,5-bis-methoxymethoxy-cyclopent-2-enone

253189-34-3

(R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester

253189-15-0

(3S,6S,7R)-4-Iodo-6,7-bis-methoxymethoxy-1-oxa-spiro[2.4]hept-4-ene

253189-34-3

(R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester

253189-16-1

(1R,4S,5R)-1-Hydroxymethyl-2-iodo-4,5-bis-methoxymethoxy-cyclopent-2-enol

253189-34-3

(R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester

253189-17-2

Acetic acid (1R,2R,5S)-2-acetoxymethyl-2,5-dihydroxy-3-iodo-cyclopent-3-enyl ester

253189-34-3

(R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester

253189-28-5

Acetic acid (1R,4S,5R)-1-acetoxymethyl-2-iodo-4,5-bis-methoxymethoxy-cyclopent-2-enyl ester

253189-34-3

(R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester

253189-30-9

Acetic acid (1R,2R,5S)-2-acetoxymethyl-5-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-3-iodo-cyclopent-3-enyl ester

253189-34-3

(R)-3-tert-Butoxycarbonylamino-3-{5-[(1S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-4-hydroxymethyl-3-iodo-cyclopent-2-enyloxy]-6-chloro-pyridin-2-yl}-propionic acid methyl ester

上游原料

Acetic acid (1R,4S,5R)-1-acetoxymethyl-2-iodo-4,5-bis-methoxymethoxy-cyclopent-2-enyl ester (4S,5R)-2-Iodo-4,5-bis-methoxymethoxy-cyclopent-2-enone (1R,4S,5R)-1-Hydroxymethyl-2-iodo-4,5-bis-methoxymethoxy-cyclopent-2-enol Acetic acid (1R,2R,5S)-2-acetoxymethyl-5-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-3-iodo-cyclopent-3-enyl ester Acetic acid (1R,2R,5S)-2-acetoxymethyl-2,5-dihydroxy-3-iodo-cyclopent-3-enyl ester (3S,6S,7R)-4-Iodo-6,7-bis-methoxymethoxy-1-oxa-spiro[2.4]hept-4-ene

下游产品

(R)-3-tert-Butoxycarbonylamino-3-{5-[(5R,6R,7S)-6-(tert-butyl-dimethyl-silanyloxy)-9-iodo-2,2-dimethyl-1,3-dioxa-spiro[4.4]non-8-en-7-yloxy]-6-chloro-pyridin-2-yl}-propionic acid