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(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

CAS号：259091-45-7

英文名：(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

分子式：C12H21NO5

分子量：259.299

合成路线

(2S,5R,1'S)-5-hydroxymethyl-2-[1'-(N-tosylamino)ethyl]tetrahydrofuran

(2S,5R,1'S)-5-hydroxymethyl-2-[1'-(N-tosylamino)ethyl]tetrahydrofuran

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

(3S,4S)-4-Dibenzylamino-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-1-yn-3-ol

(3S,4S)-4-Dibenzylamino-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-1-yn-3-ol

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

(3R,4S)-4-Dibenzylamino-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-1-yn-3-ol

(3R,4S)-4-Dibenzylamino-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-1-yn-3-ol

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

[(1S,2S)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-1-methyl-butyl]-carbamic acid tert-butyl ester

[(1S,2S)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-1-methyl-butyl]-carbamic acid tert-butyl ester

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

(2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid

上游原料

[(1S,2S)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-1-methyl-butyl]-carbamic acid tert-butyl ester (3R,4S)-4-Dibenzylamino-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-1-yn-3-ol (2S,5R,1'S)-5-hydroxymethyl-2-[1'-(N-tosylamino)ethyl]tetrahydrofuran (3S,4S)-4-Dibenzylamino-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-1-yn-3-ol

下游产品

{N-(tert-Butoxycarbonyl)glycyl}-{(2'R,5'S,1''S)-5'-(1''-aminoethyl)tetrahydrofuran-2'-carbonyl}-{(2S)-3-amino-2-benzyloxycarbonylamino methyl propionate} (S)-3-{[(2R,5S)-5-((S)-1-Amino-ethyl)-tetrahydro-furan-2-carbonyl]-amino}-2-benzyloxycarbonylamino-propionic acid methyl ester