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(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

CAS号：262297-36-9

英文名：(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

分子式：C18H19N3O7S

分子量：421.424

合成路线

3-[(2S,4R)-4-Hydroxy-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester

3-[(2S,4R)-4-Hydroxy-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester

(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

3-[(2S,4R)-4-Methanesulfonyloxy-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester

3-[(2S,4R)-4-Methanesulfonyloxy-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester

(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

3-[(2S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester

3-[(2S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester

(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

(2S,4S)-4-Acetylsulfanyl-2-(5-hydroxymethyl-isoxazol-3-yl)-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester

上游原料

3-[(2S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester 3-[(2S,4R)-4-Hydroxy-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester 3-[(2S,4R)-4-Methanesulfonyloxy-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-2-yl]-isoxazole-5-carboxylic acid ethyl ester

下游产品

(2S,4S)-2-(5-Hydroxymethyl-isoxazol-3-yl)-4-mercapto-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester (4R,5S,6S)-6-((R)-1-Hydroxy-ethyl)-3-[(3S,5S)-5-(5-hydroxymethyl-isoxazol-3-yl)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-3-ylsulfanyl]-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester