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(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

CAS号：271600-60-3

英文名：(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

分子式：C17H24BrNO4Si

分子量：414.366

合成路线

(1S,8aS)-1-((R)-1-Hydroxy-but-2-ynyl)-6-triisopropylsilanyl-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8aS)-1-((R)-1-Hydroxy-but-2-ynyl)-6-triisopropylsilanyl-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8aS)-1-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8aS)-1-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

Formic acid (S)-1-((1S,8aS)-3,7-dioxo-6-triisopropylsilanyl-1,7,8,8a-tetrahydro-oxazolo[3,4-a]pyridin-1-yl)-but-2-ynyl ester

Formic acid (S)-1-((1S,8aS)-3,7-dioxo-6-triisopropylsilanyl-1,7,8,8a-tetrahydro-oxazolo[3,4-a]pyridin-1-yl)-but-2-ynyl ester

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(S)-2-[(S)-Hydroxy-(methoxy-methyl-carbamoyl)-methyl]-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

(S)-2-[(S)-Hydroxy-(methoxy-methyl-carbamoyl)-methyl]-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(S)-2-((S)-2,2-Diethyl-5-oxo-[1,3]dioxolan-4-yl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

(S)-2-((S)-2,2-Diethyl-5-oxo-[1,3]dioxolan-4-yl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(S)-2-((S)-1-Hydroxy-2-oxo-pent-3-ynyl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

(S)-2-((S)-1-Hydroxy-2-oxo-pent-3-ynyl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(S)-2-((1S,2R)-1,2-Dihydroxy-pent-3-ynyl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

(S)-2-((1S,2R)-1,2-Dihydroxy-pent-3-ynyl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8aS)-1-((S)-1-Hydroxy-but-2-ynyl)-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8aS)-1-((S)-1-Hydroxy-but-2-ynyl)-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

(1S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

上游原料

Formic acid (S)-1-((1S,8aS)-3,7-dioxo-6-triisopropylsilanyl-1,7,8,8a-tetrahydro-oxazolo[3,4-a]pyridin-1-yl)-but-2-ynyl ester (S)-2-((S)-2,2-Diethyl-5-oxo-[1,3]dioxolan-4-yl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester (1S,8aS)-1-((S)-1-Hydroxy-but-2-ynyl)-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione (S)-2-[(S)-Hydroxy-(methoxy-methyl-carbamoyl)-methyl]-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester (1S,8aS)-1-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-but-2-ynyl]-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione (S)-2-((S)-1-Hydroxy-2-oxo-pent-3-ynyl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester (S)-2-((1S,2R)-1,2-Dihydroxy-pent-3-ynyl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester (1S,8aS)-1-((R)-1-Hydroxy-but-2-ynyl)-6-triisopropylsilanyl-8,8a-dihydro-1H-oxazolo[3,4-a]pyridine-3,7-dione

下游产品

(1S,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-1,5,6,8a-tetrahydro-oxazolo[3,4-a]pyridin-3-one (1S,7S,8R,8aR)-8-Bromo-1-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-but-2-ynyl]-7-hydroxy-hexahydro-oxazolo[3,4-a]pyridin-3-one (2aS,3S,7bS)-3-(tert-Butyl-dimethyl-silanyloxy)-4-eth-(Z)-ylidene-2a,3,4,6,7,7b-hexahydro-2-oxa-7a-aza-cyclopenta[cd]inden-1-one