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(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

CAS号：272124-29-5

英文名：(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

分子式：C28H28N6O3

分子量：496.56

合成路线

2-O-acetyl-5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonothiolactam

2-O-acetyl-5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonothiolactam

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(3S,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-<(benzyloxy)methyl>piperidin-2-one

(3S,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-<(benzyloxy)methyl>piperidin-2-one

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8S)-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydrotriazolo[4,3-a]pyridin-8-ol

(5R,6R,7R,8S)-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydrotriazolo[4,3-a]pyridin-8-ol

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonolactam

5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonolactam

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7S,8R)-8-acetoxy-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[1,2-a]pyridine

(5R,6R,7S,8R)-8-acetoxy-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[1,2-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7S,8R)-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro-8-[(methylsulfonyl)oxy][1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7S,8R)-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro-8-[(methylsulfonyl)oxy][1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

2-O-acetyl-5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonolactam

2-O-acetyl-5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonolactam

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

(5R,6R,7R,8R)-8-azido-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine

上游原料

5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonolactam (5R,6R,7S,8R)-8-acetoxy-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[1,2-a]pyridine 2-O-acetyl-5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonothiolactam (5R,6R,7R,8S)-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydrotriazolo[4,3-a]pyridin-8-ol (5R,6R,7S,8R)-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydro-8-[(methylsulfonyl)oxy][1,2,4]triazolo[4,3-a]pyridine (3S,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-<(benzyloxy)methyl>piperidin-2-one 2-O-acetyl-5-amino-3,4,6-tri-O-benzyl-5-deoxy-D-mannonolactam

下游产品

(5R,6R,7S,8S)-8-amino-5,6,7,8-tetrahydro-5-(hydroxymethyl)[1,2,4]triazolo[4,3-a]pyridine-6,7-diol