19-去甲-17a-孕甾-1,3,5(10)-三烯-20-炔-3,17-二醇 3-(2-丙烷磺酸酯)

Ethinyl estradiol sulfonate (EES) (brand name Turisteron), also known as ethinyl estradiol isopropylsulfonate or ethinyl estradiol propanesulfate, as well as 17α-ethinyl-3-isopropylsulfonyloxyestradiol, is a synthetic, steroidal estrogen that is marketed in Germany. It is an ester of ethinyl estradiol, and acts as a long-acting (half-life of six days), orally active depot form of the drug. EES is used in the treatment of advanced breast and prostate cancers. The drug is very potent (used clinically at a dosage of 1–2 mg weekly via intramuscular injection) and a powerful antigonadotropin, capable of suppressing circulating testosterone concentrations to levels comparable to those seen with castration (less than 1–3% of initial values). As such, EES is a strong functional antiandrogen.