百科

N-[(R)-2-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-1-hydroxymethyl-ethyl]-N-[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-4-methyl-benzenesulfonamide

N-[(R)-2-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-1-hydroxymethyl-ethyl]-N-[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-4-methyl-benzenesulfonamide

CAS号：295337-92-7

英文名：N-[(R)-2-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-1-hydroxymethyl-ethyl]-N-[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-4-methyl-benzenesulfonamide

分子式：C44H57NO7SSi

分子量：772.076

合成路线

(S)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-(toluene-4-sulfonylamino)-propionic acid methyl ester

(S)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-(toluene-4-sulfonylamino)-propionic acid methyl ester

N-[(R)-2-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-1-hydroxymethyl-ethyl]-N-[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-4-methyl-benzenesulfonamide

N-[(R)-2-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-1-hydroxymethyl-ethyl]-N-[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-4-methyl-benzenesulfonamide

(S)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-[[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-(toluene-4-sulfonyl)-amino]-propionic acid methyl ester

(S)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-[[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-(toluene-4-sulfonyl)-amino]-propionic acid methyl ester

N-[(R)-2-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-1-hydroxymethyl-ethyl]-N-[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-4-methyl-benzenesulfonamide

N-[(R)-2-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-1-hydroxymethyl-ethyl]-N-[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-4-methyl-benzenesulfonamide

上游原料

(S)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-[[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-(toluene-4-sulfonyl)-amino]-propionic acid methyl ester (S)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-(toluene-4-sulfonylamino)-propionic acid methyl ester

下游产品

2-(4-{(R)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-[((E)-5-chloro-pent-3-enyl)-(toluene-4-sulfonyl)-amino]-propoxy}-butyl)-malonic acid dimethyl ester 2-(4-{(R)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-[((E)-5-hydroxy-pent-3-enyl)-(toluene-4-sulfonyl)-amino]-propoxy}-butyl)-malonic acid dimethyl ester N-[(R)-2-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-1-(4-iodo-butoxymethyl)-ethyl]-N-[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-4-methyl-benzenesulfonamide 2-(4-{(R)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2-[[(E)-5-(tert-butyl-diphenyl-silanyloxy)-pent-3-enyl]-(toluene-4-sulfonyl)-amino]-propoxy}-butyl)-malonic acid dimethyl ester (E)-(R)-3-(6-Benzyloxymethyl-tetrahydro-pyran-2-yloxymethyl)-4-(toluene-4-sulfonyl)-1-oxa-4-aza-cyclotetradec-7-ene-10,10-dicarboxylic acid dimethyl ester