百科

(2S,3S,4R)-3-hydroxy-4-hydroxymethyl-4-O-methoxalyloxy-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

CAS号：296250-80-1

英文名：(2S,3S,4R)-3-hydroxy-4-hydroxymethyl-4-O-methoxalyloxy-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

分子式：C28H46O11SSi2

分子量：646.894

合成路线

223591-10-4

(2R,3S,4S)-3-benzyloxy-4-benzyloxymethyl-2-formyl-4-hydroxytetrahydrofuran

296250-80-1

(2S,3S,4R)-3-hydroxy-4-hydroxymethyl-4-O-methoxalyloxy-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

219854-35-0

methyl 3,5-di-O-benzyl-4-C-methylsulfonyloxymethyl-α,β-D-ribofuranoside

296250-80-1

(2S,3S,4R)-3-hydroxy-4-hydroxymethyl-4-O-methoxalyloxy-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

223590-98-5

(1S,3RS,4R,7S)-7-benzyloxy-1-benzyloxymethyl-3-methoxy-2,5-dioxabicyclo[2.2.1]heptane

296250-80-1

(2S,3S,4R)-3-hydroxy-4-hydroxymethyl-4-O-methoxalyloxy-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

223590-99-6

(2S,3S,4S)-3-benzyloxy-4-benzyloxymethyl-2-hydroxymethyl-4-hydroxytetrahydrofuran

296250-80-1

(2S,3S,4R)-3-hydroxy-4-hydroxymethyl-4-O-methoxalyloxy-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

223591-06-8

(2S,3S,4S)-3-benzyloxy-4-benzyloxymethyl-2-(p-toluenesulfonyl)oxymethyl-4-hydroxytetrahydrofuran

296250-80-1

(2S,3S,4R)-3-hydroxy-4-hydroxymethyl-4-O-methoxalyloxy-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

296250-78-7

(2S,3S,4S)-3,4-dihydroxy-4-hydroxymethyl-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

296250-80-1

(2S,3S,4R)-3-hydroxy-4-hydroxymethyl-4-O-methoxalyloxy-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran

上游原料

(2S,3S,4S)-3-benzyloxy-4-benzyloxymethyl-2-(p-toluenesulfonyl)oxymethyl-4-hydroxytetrahydrofuran methyl 3,5-di-O-benzyl-4-C-methylsulfonyloxymethyl-α,β-D-ribofuranoside (2S,3S,4S)-3-benzyloxy-4-benzyloxymethyl-2-hydroxymethyl-4-hydroxytetrahydrofuran (2R,3S,4S)-3-benzyloxy-4-benzyloxymethyl-2-formyl-4-hydroxytetrahydrofuran (2S,3S,4S)-3,4-dihydroxy-4-hydroxymethyl-2-((p-toluenesulfonyloxy)methyl)tetrahydrofuran (1S,3RS,4R,7S)-7-benzyloxy-1-benzyloxymethyl-3-methoxy-2,5-dioxabicyclo[2.2.1]heptane

下游产品

(2S,3S,4S)-4-(4,4'-dimethoxytrityl)oxymethyl-3-hydroxy-2-((thymin-1-yl)methyl)tetrahydrofuran (2S,3S,4R)-3-hydroxy-4-hydroxymethyl-2-((thymin-1-yl)methyl)tetrahydrofuran (2S,3S,4S)-3-hydroxy-4-hydroxymethyl-3-O,O-(hydroxymethyl)-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-((thymin-1-yl)methyl)tetrahydrofuran