百科

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

CAS号：299177-89-2

英文名：{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

分子式：C29H51NO7Si2

分子量：581.889

合成路线

(1R,2R)-2-t-butyldimethylsilyloxymethylcyclohexanol

(1R,2R)-2-t-butyldimethylsilyloxymethylcyclohexanol

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

(R)-2-t-butyldimethylsilyloxymethyl-1-trimethylsilyloxycyclohexene

(R)-2-t-butyldimethylsilyloxymethyl-1-trimethylsilyloxycyclohexene

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

ethyl (1S,2R)-2-hydroxycyclohexanecarboxylate

ethyl (1S,2R)-2-hydroxycyclohexanecarboxylate

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

2-((hydroxy-24-trioxidaneyl)oxy)-1-((2,3,3-trihydroxy-24,34-tetraoxidaneyl)peroxy)-1H-13,24,33-hexaoxine

2-((hydroxy-24-trioxidaneyl)oxy)-1-((2,3,3-trihydroxy-24,34-tetraoxidaneyl)peroxy)-1H-13,24,33-hexaoxine

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester

上游原料

(R)-2-t-butyldimethylsilyloxymethyl-1-trimethylsilyloxycyclohexene (1R,2R)-2-t-butyldimethylsilyloxymethylcyclohexanol ethyl (1S,2R)-2-hydroxycyclohexanecarboxylate

下游产品

allyl (4S,8S,9R,10S)-4-[(benzothiazol-2-yl)thiomethyl]-10-[(R)-1-hydroxyethyl]-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-4-[N-allyloxycarbonyl-N-(2-thiazolyl)aminomethyl]-10-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-4-[(benzothiazol-2-yl)thiomethyl]-10-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-4-(N,N-bis(allyloxycarbonyl)aminomethyl)-10-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-4-[[1,2-bis(allyloxycarbonyl)guanidino]methyl]-10-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-10-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-4-t-butyldimethylsilyloxymethyl-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-10-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-4-hydroxymethyl-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-4-[N-allyloxycarbonyl-N-(2-thiazolyl)aminomethyl]-10-[(R)-1-hydroxyethyl]-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-4-(N,N-bis(allyloxycarbonyl)aminomethyl)-10-[(R)-1-hydroxyethyl]-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate allyl (4S,8S,9R,10S)-4-[[1,2-bis(allyloxycarbonyl)guanidino]methyl]-10-[(R)-1-hydroxyethyl]-11-oxo-azatricyclo[7.2.0.03,8]undec-2-ene-2-carboxylate