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4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

CAS号：299217-33-7

英文名：4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

分子式：C49H58N4O10

分子量：863.006

合成路线

3-(3'-N-BOC-aminobenzyloxy)-5-hydroxybenzyl alcohol

3-(3'-N-BOC-aminobenzyloxy)-5-hydroxybenzyl alcohol

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

3-(3'-N-BOC-aminobenzyloxy)-5-i-pentyloxybenzyl bromide

3-(3'-N-BOC-aminobenzyloxy)-5-i-pentyloxybenzyl bromide

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

3-(3'-N-BOC-aminobenzyloxy)-5-i-pentyloxybenzyl alcohol

3-(3'-N-BOC-aminobenzyloxy)-5-i-pentyloxybenzyl alcohol

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

8-[3'-(3-i-pentyloxy)-5'-(3''-N-BOC-aminobenzyloxy)benzyloxy]-2-[1-(4'''-acetoxyphenyl)ethyl]quinolinone

8-[3'-(3-i-pentyloxy)-5'-(3''-N-BOC-aminobenzyloxy)benzyloxy]-2-[1-(4'''-acetoxyphenyl)ethyl]quinolinone

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

8-[3'-(3-i-pentyloxy)-5'-(3''-aminobenzyloxy)benzyloxy]-2-[1-(4'''-acetoxyphenyl)ethyl]quinolinone

8-[3'-(3-i-pentyloxy)-5'-(3''-aminobenzyloxy)benzyloxy]-2-[1-(4'''-acetoxyphenyl)ethyl]quinolinone

N,N'-bis-Boc-S-methyl-isothiourea

N,N'-bis-Boc-S-methyl-isothiourea

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

8-[3'-(i-pentyloxy)-5'-(3''-N-BOC-aminobenzyloxy)benzyloxy]-2-[1H]-quinolinone

8-[3'-(i-pentyloxy)-5'-(3''-N-BOC-aminobenzyloxy)benzyloxy]-2-[1H]-quinolinone

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

4-(2-(8-((3-((3-(2,3-bis(tert-butoxycarbonyl)guanidino)benzyl)oxy)-5-(isopentyloxy)benzyl)oxy)-2-oxoquinolin-1(2H)-yl)ethyl)phenyl acetate

上游原料

3-(3'-N-BOC-aminobenzyloxy)-5-hydroxybenzyl alcohol N,N'-bis-Boc-S-methyl-isothiourea 3-(3'-N-BOC-aminobenzyloxy)-5-i-pentyloxybenzyl bromide 8-[3'-(3-i-pentyloxy)-5'-(3''-aminobenzyloxy)benzyloxy]-2-[1-(4'''-acetoxyphenyl)ethyl]quinolinone 3-(3'-N-BOC-aminobenzyloxy)-5-i-pentyloxybenzyl alcohol 8-[3'-(3-i-pentyloxy)-5'-(3''-N-BOC-aminobenzyloxy)benzyloxy]-2-[1-(4'''-acetoxyphenyl)ethyl]quinolinone 8-[3'-(i-pentyloxy)-5'-(3''-N-BOC-aminobenzyloxy)benzyloxy]-2-[1H]-quinolinone

下游产品