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9-[(acetoxy)methyl]-6,7,9,14,14a,15-hexahydro-7-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-(6S,7S,9R,14aS,15R)-(-)-6,15-imino-4H-isoquino[3,2-b][3]benzazocine-1,4,10,13(5H)-tetrone

9-[(acetoxy)methyl]-6,7,9,14,14a,15-hexahydro-7-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-(6S,7S,9R,14aS,15R)-(-)-6,15-imino-4H-isoquino[3,2-b][3]benzazocine-1,4,10,13(5H)-tetrone

CAS号:304852-37-7
英文名:9-[(acetoxy)methyl]-6,7,9,14,14a,15-hexahydro-7-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-(6S,7S,9R,14aS,15R)-(-)-6,15-imino-4H-isoquino[3,2-b][3]benzazocine-1,4,10,13(5H)-tetrone
分子式:C27H30N2O9
分子量:526.535
上游原料
{(S)-2-((1R,3S)-8-Allyloxy-1-allyloxymethyl-3-hydroxymethyl-5,7-dimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-1-[5-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethoxy-3-methyl-benzyl]-2-oxo-ethyl}-carbamic acid tert-butyl ester {2-[8-allyloxy-1-allyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-5,7-dimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin-2-yl]-1-[5-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethoxy-3-methyl-benzyl]-2-oxo-ethyl}-carbamic acid tert-butyl ester (1R,3S)-8-Allyloxy-1-allyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-5,7-dimethoxy-6-methyl-1,2,3,4-tetrahydro-isoquinoline (1R,3S,6R,11aS)-7-Allyloxy-6-allyloxymethyl-3-[5-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethoxy-3-methyl-benzyl]-1-hydroxy-8,10-dimethoxy-9-methyl-4-oxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-b]isoquinoline-2-carboxylic acid tert-butyl ester (6S,9R,14aS,15R)-10-(allyloxy)-9-((allyloxy)methyl)-1-hydroxy-2,4,11,13-tetramethoxy-3,12-dimethyl-5,6,9,14,14a,15-hexahydro-7H-6,15-epiminobenzo[4,5]azocino[1,2-b]isoquinolin-7-one (6S,9R,14aS,15R)-10-(allyloxy)-9-((allyloxy)methyl)-1-hydroxy-2,4,11,13-tetramethoxy-3,12,16-trimethyl-5,6,9,14,14a,15-hexahydro-7H-6,15-epiminobenzo[4,5]azocino[1,2-b]isoquinolin-7-one (1R,3S)-8-Allyloxy-1-allyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-5,7-dimethoxy-6-methyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester (S)-1-[(1R,3S)-8-Allyloxy-1-allyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-5,7-dimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin-2-yl]-2-amino-3-[5-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethoxy-3-methyl-phenyl]-propan-1-one (1R,3S,6R,11aS)-7-Allyloxy-6-allyloxymethyl-1-hydroxy-3-(5-hydroxy-2,4-dimethoxy-3-methyl-benzyl)-8,10-dimethoxy-9-methyl-4-oxo-1,3,4,6,11,11a-hexahydro-pyrazino[1,2-b]isoquinoline-2-carboxylic acid tert-butyl ester (6S,7R,9R,14aS,15R)-1,10-dihydroxy-9-(hydroxymethyl)-2,4,11,13-tetramethoxy-3,12,16-trimethyl-6,7,9,14,14a,15-hexahydro-5H-6,15-epiminobenzo[4,5]azocino[1,2-b]isoquinoline-7-carbonitrile (S)-3-[5-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethoxy-3-methyl-phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid (S)-N-(((6S,7R,9R,14aS,15R)-7-cyano-1-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,7,9,10,13,14,14a,15-octahydro-5H-6,15-epiminobenzo[4,5]azocino[1,2-b]isoquinolin-9-yl)methyl)-2-(3-phenylthioureido)propanamide (1R,3S)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-8-hydroxy-1-hydroxymethyl-5,7-dimethoxy-6-methyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 3,4-dimethoxy-5-methyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate