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格尔德霉素
CAS号:30562-34-6
英文名:geldanamycin
分子式:C29H40N2O9
分子量:560.636
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上游原料
474411-07-9
(2R,3S,5R)-2-hydroxy-3-methoxy-5-methyl-6-(5-nitro-2,3,6-trimethoxy-phenyl)-hexanoic acid methyl ester
52762-28-4
[(8E,12Z,14E)-6,22-dihydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,21-trioxo-17-azabicyclo[16.3.1]docosa-1(22),8,12,14,18-pentaen-10-yl] carbamate
326606-16-0
(3S,5S,6S)-3-[(1S,3R)-1-hydroxy-3-methyl-4-(5-nitro-2,3,6-trimethoxy-phenyl)-butyl]-5,6-bis-(4-methoxy-phenyl)-[1,4]dioxan-2-one
474411-09-1
(3R,4S,6R)-3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-6-methyl-7-(5-nitro-2,3,6-trimethoxy-phenyl)-heptan-2-one
474411-08-0
(2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-5-methyl-6-(5-nitro-2,3,6-trimethoxy-phenyl)-hexanal
474411-21-7
(2E,4S,5R,6S,8R)-5-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-9-(3-nitro-2,5,6-trimethoxy-phenyl)-2,4,8-trimethyl-non-2-en-1-ol
76045-71-1
3-氨基-5-羟基苯甲酸
474411-20-6
(2S,3R,4S,6R)-3-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-4-methoxy-7-(5-nitro-2,3,6-trimethoxy-phenyl)-heptan-1-ol
474411-01-3
(2R,3S,4E,6S,7R,8S,10R)-7-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,8-dimethoxy-11-(3-nitro-2,5,6-trimethoxy-phenyl)-4,6,10-trimethyl-undec-4-enoic acid methyl ester
474411-00-2
(2R,3S,4E,6S,7R,8S,10R)-7-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,8-dimethoxy-11-(3-nitro-2,5,6-trimethoxy-phenyl)-4,6,10-trimethyl-undec-4-enoic acid (1R,2S)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl ester
625450-93-3
(E)-(2R,3S,6S,7R,8S,10R)-7-(tert-Butyl-dimethyl-silanyloxy)-2,8-dimethoxy-4,6,10-trimethyl-3-triethylsilanyloxy-11-(2,3,6-trimethoxy-5-nitro-phenyl)-undec-4-enal
474410-96-3
(3R,4S,6R)-3-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-4-methoxy-7-(5-nitro-2,3,6-trimethoxy-phenyl)-hept-1-ene
474410-95-2
(3R,4S,6R)-3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-6-methyl-7-(5-nitro-2,3,6-trimethoxy-phenyl)-heptan-2-ol
474410-94-1
(2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-5-methyl-6-(5-nitro-2,3,6-trimethoxy-phenyl)-hexanoic acid methyl ester
474411-15-9
(2Z,4S,5S,6E,8S,9R,10S,12R)-9-((tert-butyldimethylsilyl)oxy)-4,10-dimethoxy-6,8,12-trimethyl-5-((triethylsilyl)oxy)-13-(2,3,6-trimethoxy-5-nitrophenyl)trideca-2,6-dienal
474410-93-0
(2R,3S,5R)-2-[(1S,2S)-2-hydroxy-1,2-bis-(4-methoxy-phenyl)-ethoxy]-3-methoxy-5-methyl-6-(5-nitro-2,3,6-trimethoxy-phenyl)-hexanoic acid methyl ester
474411-14-8
(2Z,4S,5S,6E,8S,9R,12R,10S)-9-(tert-butyl-dimethyl-silanyloxy)-4,10-dimethoxy-13-(3-nitro-2,5,6-trimethoxy-phenyl)-6,8,12-trimethyl-5-(triethyl-silanyloxy)-trideca-2,6-dien-1-ol
474411-19-3
(4E,6Z,8S,9S,10E,12S,13R,14S,16R) carbamic acid 13-(tert-butyl-dimethyl-silanyloxy)-8,14,19,20,22-pentamethoxy-4,10,12,16-tetramethyl-3-oxo-2-aza-bicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-9-yl ester
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上游原料
(2R,3S,5R)-2-hydroxy-3-methoxy-5-methyl-6-(5-nitro-2,3,6-trimethoxy-phenyl)-hexanoic acid methyl ester
[(8E,12Z,14E)-6,22-dihydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,21-trioxo-17-azabicyclo[16.3.1]docosa-1(22),8,12,14,18-pentaen-10-yl] carbamate
(3S,5S,6S)-3-[(1S,3R)-1-hydroxy-3-methyl-4-(5-nitro-2,3,6-trimethoxy-phenyl)-butyl]-5,6-bis-(4-methoxy-phenyl)-[1,4]dioxan-2-one
(3R,4S,6R)-3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-6-methyl-7-(5-nitro-2,3,6-trimethoxy-phenyl)-heptan-2-one
(2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-5-methyl-6-(5-nitro-2,3,6-trimethoxy-phenyl)-hexanal
(2E,4S,5R,6S,8R)-5-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-9-(3-nitro-2,5,6-trimethoxy-phenyl)-2,4,8-trimethyl-non-2-en-1-ol
3-氨基-5-羟基苯甲酸
(2S,3R,4S,6R)-3-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-4-methoxy-7-(5-nitro-2,3,6-trimethoxy-phenyl)-heptan-1-ol
(2R,3S,4E,6S,7R,8S,10R)-7-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,8-dimethoxy-11-(3-nitro-2,5,6-trimethoxy-phenyl)-4,6,10-trimethyl-undec-4-enoic acid methyl ester
(2R,3S,4E,6S,7R,8S,10R)-7-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,8-dimethoxy-11-(3-nitro-2,5,6-trimethoxy-phenyl)-4,6,10-trimethyl-undec-4-enoic acid (1R,2S)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl ester
(E)-(2R,3S,6S,7R,8S,10R)-7-(tert-Butyl-dimethyl-silanyloxy)-2,8-dimethoxy-4,6,10-trimethyl-3-triethylsilanyloxy-11-(2,3,6-trimethoxy-5-nitro-phenyl)-undec-4-enal
(3R,4S,6R)-3-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-4-methoxy-7-(5-nitro-2,3,6-trimethoxy-phenyl)-hept-1-ene
(3R,4S,6R)-3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-6-methyl-7-(5-nitro-2,3,6-trimethoxy-phenyl)-heptan-2-ol
(2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-5-methyl-6-(5-nitro-2,3,6-trimethoxy-phenyl)-hexanoic acid methyl ester
(2Z,4S,5S,6E,8S,9R,10S,12R)-9-((tert-butyldimethylsilyl)oxy)-4,10-dimethoxy-6,8,12-trimethyl-5-((triethylsilyl)oxy)-13-(2,3,6-trimethoxy-5-nitrophenyl)trideca-2,6-dienal
(2R,3S,5R)-2-[(1S,2S)-2-hydroxy-1,2-bis-(4-methoxy-phenyl)-ethoxy]-3-methoxy-5-methyl-6-(5-nitro-2,3,6-trimethoxy-phenyl)-hexanoic acid methyl ester
(2Z,4S,5S,6E,8S,9R,12R,10S)-9-(tert-butyl-dimethyl-silanyloxy)-4,10-dimethoxy-13-(3-nitro-2,5,6-trimethoxy-phenyl)-6,8,12-trimethyl-5-(triethyl-silanyloxy)-trideca-2,6-dien-1-ol
(4E,6Z,8S,9S,10E,12S,13R,14S,16R) carbamic acid 13-(tert-butyl-dimethyl-silanyloxy)-8,14,19,20,22-pentamethoxy-4,10,12,16-tetramethyl-3-oxo-2-aza-bicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-9-yl ester
(3S,5S,6S)-3-[(1S,3R)-1-methoxy-3-methyl-4-(5-nitro-2,3,6-trimethoxy-phenyl)-butyl]-5,6-bis-(4-methoxy-phenyl)-[1,4]dioxan-2-one
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-8,14,19,20,22-pentamethoxy-4,10,12,16-tetramethyl-2-aza-bicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-3-one
(2R,3S,4E,6S,7R,8S,10R)-7-(tert-butyl-dimethyl-silanyloxy)-2,8-dimethoxy-11-(3-nitro-2,5,6-trimethoxy-phenyl)-4,6,10-trimethyl-3-(triethyl-silanyloxy)-undec-4-enoic acid methyl ester
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-(tert-butyl-dimethyl-silanyloxy)-8,14,19,20,22-pentamethoxy-4,10,12,16-tetramethyl-9-(triethyl-silanyloxy)-2-aza-bicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-3-one
(2R,3R,4S,6R)-3-(tert-Butyl-dimethyl-silanyloxy)-4-methoxy-2,6-dimethyl-7-(2,3,6-trimethoxy-5-nitro-phenyl)-heptanal
(2S,3R,4S,6R)-2,6-dimethyl-4-methoxy-7-(5-nitro-2,3,6-trimethoxy-phenyl)-heptane-1,3-diol-1,3-bis-(tert-butyl-dimethyl-silyl) ether
(2E,4Z,6S,7S,8E,10S,11R,12S,14R)-15-(3-amino-2,5,6-trimethoxy-phenyl)-11-(tert-butyl-dimethyl-silanyloxy)-6,12-dimethoxy-2,8,10,14-tetramethyl-7-(triethyl-silanyloxy)-pentadeca-2,4,8-trienoic acid allyl ester
(3R,4S,6R)-2,6-dimethyl-3-hydroxy-4-methoxy-7-(5-nitro-2,3,6-trimethoxy-phenyl)-hept-1-ene
(2E,4S,5R,6S,8R)-5-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-9-(3-nitro-2,5,6-trimethoxy-phenyl)-2,4,8-trimethyl-non-2-enal
(2E,4S,5R,6S,8R)-5-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-9-(3-nitro-2,5,6-trimethoxy-phenyl)-2,4,8-trimethyl-non-2-enoic acid ethyl ester
(2E,4Z,6S,7S,8E,10S,11R,12S,14R)-15-(3-amino-2,5,6-trimethoxy-phenyl)-11-(tert-butyl-dimethyl-silanyloxy)-6,12-dimethoxy-2,8,10,14-tetramethyl-7-(triethyl-silanyloxy)-pentadeca-2,4,8-trienoic acid
(2S,3R,4S,6R)-2,6-dimethyl-4-methoxy-7-(5-nitro-2,3,6-trimethoxy-phenyl)-heptane-1,3-diol
下游产品
阿螺旋霉素
替拉替尼
(10E)-19-氨基-13-羟基-8,14-二甲氧基-4,10,12,16-四甲基-3,20,22-三氧代-2-氮杂双环[16.3.1]二十二碳-1(21),4,6,10,18-五烯-9-基氨基甲酸酯