百科

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

CAS号：306725-96-2

英文名：(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

分子式：C29H42O8Si

分子量：546.724

合成路线

(2S,3S)-1-Allyloxy-4-benzyloxy-butane-2,3-diol

(2S,3S)-1-Allyloxy-4-benzyloxy-butane-2,3-diol

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

(4S,5S)-4-benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-1,3-dioxolane

(4S,5S)-4-benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-1,3-dioxolane

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

((2S,3S)-4-Allyloxy-2,3-bis-trimethylsilanyloxy-butoxymethyl)-benzene

((2S,3S)-4-Allyloxy-2,3-bis-trimethylsilanyloxy-butoxymethyl)-benzene

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

(2S,3S,8R,9S,10R)-9,10-Bis-allyloxy-2-allyloxymethyl-8-benzyloxy-3-benzyloxymethyl-1,4,6-trioxa-spiro[4.5]decane

(2S,3S,8R,9S,10R)-9,10-Bis-allyloxy-2-allyloxymethyl-8-benzyloxy-3-benzyloxymethyl-1,4,6-trioxa-spiro[4.5]decane

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

(2S,3S,5S,8R,9R,10R)-8-Benzyloxy-2-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-1,4,6-trioxa-spiro[4.5]decane-9,10-diol

上游原料

(4S,5S)-4-benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-1,3-dioxolane (2S,3S,8R,9S,10R)-9,10-Bis-allyloxy-2-allyloxymethyl-8-benzyloxy-3-benzyloxymethyl-1,4,6-trioxa-spiro[4.5]decane ((2S,3S)-4-Allyloxy-2,3-bis-trimethylsilanyloxy-butoxymethyl)-benzene (2S,3S)-1-Allyloxy-4-benzyloxy-butane-2,3-diol

下游产品

(2S,3S,5S,8R,9S,10R)-2-(((tert-butyldimethylsilyl)oxy)methyl)-8-hydroxy-3-(hydroxymethyl)-1,4,6-trioxaspiro[4.5]decane-9,10-diyl dibenzoate (2S,3S,5S,8R,9S,10R)-8-((benzyloxy)methoxy)-2-((R)-hydroxy(thiazol-2-yl)methyl)-3-(((triisopropylsilyl)oxy)methyl)-1,4,6-trioxaspiro[4.5]decane-9,10-diyl dibenzoate (2R,3S,5S,8R,9S,10R)-8-((benzyloxy)methoxy)-2-((R)-((4-bromobenzoyl)oxy)(thiazol-2-yl)methyl)-3-(((triisopropylsilyl)oxy)methyl)-1,4,6-trioxaspiro[4.5]decane-9,10-diyl bis(4-bromobenzoate) (2S,3S,5S,8R,9S,10R)-8-((benzyloxy)methoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)-3-(((triisopropylsilyl)oxy)methyl)-1,4,6-trioxaspiro[4.5]decane-9,10-diyl dibenzoate (2S,3S,5R,8R,9S,10R)-8-((benzyloxy)methoxy)-2-(hydroxymethyl)-3-(((triisopropylsilyl)oxy)methyl)-1,4,6-trioxaspiro[4.5]decane-9,10-diyl dibenzoate (2S,3S,5S,8R,9R,10R)-8-Benzyloxymethoxy-2-((R)-hydroxy-thiazol-2-yl-methyl)-3-triisopropylsilanyloxymethyl-1,4,6-trioxa-spiro[4.5]decane-9,10-diol