百科

(2R,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentan-4-olide

(2R,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentan-4-olide

CAS号：307298-18-6

英文名：(2R,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentan-4-olide

分子式：C12H21F3O3Si

分子量：298.374

合成路线

(Z)/(E)-ethyl 3-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-bromo-2-propenoate

(Z)/(E)-ethyl 3-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-bromo-2-propenoate

(2R,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentan-4-olide

(2R,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentan-4-olide

上游原料

(Z)/(E)-ethyl 3-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-bromo-2-propenoate

下游产品

(2R,4S)-5-(tert-butyldimethylsilyl)-2,3-dideoxy-2-trifluoromethylpentofuranose (2R,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentane-1,4-diol (2'R)-α-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine Methanesulfonic acid (1S,3R)-1-(tert-butyl-dimethyl-silanyloxymethyl)-4,4,4-trifluoro-3-methanesulfonyloxymethyl-butyl ester (2'R)-α-D-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylthymidine (2'R)-α-D-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethyluridine (2'R)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine (2'R)-β-D-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylthymidine (2R,4S)-tert-butyldimethyl-4-(trifluoromethyl-tetrahydro-thiophen-2-ylmethoxy)silane (2'R)-β-D-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethyluridine (2R,4S)-1-O-acetyl-5-(tert-butyldimethylsilyl)-2,3-dideoxy-2-trifluoromethylpentofuranose tert-Butyl-dimethyl-((2R,4S)-1-oxo-4-trifluoromethyl-tetrahydro-1λ4-thiophen-2-ylmethoxy)-silane