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(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

CAS号：307298-37-9

英文名：(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

分子式：C23H30F3N3O4Si

分子量：497.583

合成路线

(2R,4S/2S,4S)-5-hydroxy-2-trifluoromethylpentan-4-olide

(2R,4S/2S,4S)-5-hydroxy-2-trifluoromethylpentan-4-olide

(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

(Z)/(E)-ethyl 3-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-bromo-2-propenoate

(Z)/(E)-ethyl 3-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-bromo-2-propenoate

(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

(2S,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentan-4-olide

(2S,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentan-4-olide

(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

(2'S)-β-D-N4-benzoyl-5'-(tert-butyldimethylsilyl)-2',3'-dideoxy-2'-trifluoromethylcytidine

上游原料

(2R,4S/2S,4S)-5-hydroxy-2-trifluoromethylpentan-4-olide (Z)/(E)-ethyl 3-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-bromo-2-propenoate (2S,4S)-5-(tert-butyldimethylsiloxy)-2-trifluoromethylpentan-4-olide

下游产品

N-[1-((2R,3S,5S)-5-Hydroxymethyl-3-trifluoromethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide