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4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

CAS号：312728-24-8

英文名：4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

分子式：C20H41NO6Si

分子量：419.628

合成路线

5-acetoxy-4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-pentanoic acid tert-butyl ester

5-acetoxy-4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-pentanoic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

3(S)-hydroxy-3-[1-(1'(S)-α-methylbenzyl)-aziridin-2(R)-yl]-propionic acid tert-butyl ester

3(S)-hydroxy-3-[1-(1'(S)-α-methylbenzyl)-aziridin-2(R)-yl]-propionic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

3(S)-(tert-butyldimethylsilanyloxy)-3-[1-(1'(S)-α-methylbenzyl)-aziridin-2(R)-yl]-propionic acid tert-butyl ester

3(S)-(tert-butyldimethylsilanyloxy)-3-[1-(1'(S)-α-methylbenzyl)-aziridin-2(R)-yl]-propionic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

5-acetoxy-3(S)-(tert-butyldimethylsilanyloxy)-4(R)-(1'(S)-α-methylbenzylamino)-pentanoic acid tert-butyl ester

5-acetoxy-3(S)-(tert-butyldimethylsilanyloxy)-4(R)-(1'(S)-α-methylbenzylamino)-pentanoic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-5-hydroxy-pentanoic acid tert-butyl ester

上游原料

5-acetoxy-3(S)-(tert-butyldimethylsilanyloxy)-4(R)-(1'(S)-α-methylbenzylamino)-pentanoic acid tert-butyl ester 5-acetoxy-4(R)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-pentanoic acid tert-butyl ester 3(S)-hydroxy-3-[1-(1'(S)-α-methylbenzyl)-aziridin-2(R)-yl]-propionic acid tert-butyl ester 3(S)-(tert-butyldimethylsilanyloxy)-3-[1-(1'(S)-α-methylbenzyl)-aziridin-2(R)-yl]-propionic acid tert-butyl ester

下游产品

2(S)-tert-butoxycarbonylamino-3(S)-(tert-butyldimethylsilanyloxy)-pentanedioic acid 5-tert-butyl ester 1-methyl ester