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allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate

allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate

CAS号：329786-83-6
英文名：allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
分子式：C43H78Cl3N5O11Si2
分子量：1003.64
合成路线
(3S,5R)-5-Hydroxy-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester
262363-89-3
(3S,5R)-5-Hydroxy-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
329786-83-6
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
(3S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester
262363-91-7
(3S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
329786-83-6
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
(3R,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester
262363-86-0
(3R,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
329786-83-6
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
(S)-2-(9H-Fluoren-9-ylmethoxycarbonyloxy)-3-methyl-butyric acid allyl ester
329786-79-0
(S)-2-(9H-Fluoren-9-ylmethoxycarbonyloxy)-3-methyl-butyric acid allyl ester
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
329786-83-6
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
di-tert-butyl 1-((3R,5R)-5-(bromomethyl)-2-oxotetrahydrofuran-3-yl)hydrazine-1,2-dicarboxylate
262363-90-6
di-tert-butyl 1-((3R,5R)-5-(bromomethyl)-2-oxotetrahydrofuran-3-yl)hydrazine-1,2-dicarboxylate
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
329786-83-6
allyl O-(tert-butyldimethylsilyl)-N-(((3R,5R)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-3-methyl-2-((((2,2,2-trichloroethoxy)carbonyl)-D-valyl)oxy)butanoyl)hexahydropyridazine-3-carbonyl)-L-leucyl)-D-threoninate
上游原料
(3R,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester (3S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester di-tert-butyl 1-((3R,5R)-5-(bromomethyl)-2-oxotetrahydrofuran-3-yl)hydrazine-1,2-dicarboxylate (3S,5R)-5-Hydroxy-tetrahydro-pyridazine-1,2,3-tricarboxylic acid 1,2-di-tert-butyl ester 3-methyl ester (S)-2-(9H-Fluoren-9-ylmethoxycarbonyloxy)-3-methyl-butyric acid allyl ester
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