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{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

CAS号：331942-63-3

英文名：{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

分子式：C23H38NO6P

分子量：455.525

合成路线

((2S,4R)-5-Hydroxy-2,4-dimethyl-pentyl)-((R)-1-phenyl-ethyl)-carbamic acid tert-butyl ester

((2S,4R)-5-Hydroxy-2,4-dimethyl-pentyl)-((R)-1-phenyl-ethyl)-carbamic acid tert-butyl ester

{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

(2S,4R)-5-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanoic acid ((R)-1-phenyl-ethyl)-amide

(2S,4R)-5-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanoic acid ((R)-1-phenyl-ethyl)-amide

{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

3,5-dimethyl-tetrahydropyran-2-one

3,5-dimethyl-tetrahydropyran-2-one

{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

{(3R,5S)-6-[tert-Butoxycarbonyl-((R)-1-phenyl-ethyl)-amino]-3,5-dimethyl-2-oxo-hexyl}-phosphonic acid dimethyl ester

上游原料

((2S,4R)-5-Hydroxy-2,4-dimethyl-pentyl)-((R)-1-phenyl-ethyl)-carbamic acid tert-butyl ester (2S,4R)-5-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanoic acid ((R)-1-phenyl-ethyl)-amide 3,5-dimethyl-tetrahydropyran-2-one

下游产品

[(E)-(2S,4R,8R,9S,11S)-8,13-Bis-(tert-butyl-dimethyl-silanyloxy)-9-(4-methoxy-benzyloxy)-2,4,11-trimethyl-5-oxo-tridec-6-enyl]-((R)-1-phenyl-ethyl)-carbamic acid tert-butyl ester [(E)-(2S,4R,8R,9S,11R)-8-(tert-Butyl-dimethyl-silanyloxy)-9-hydroxy-2,4,11,15-tetramethyl-5,13-dioxo-hexadeca-6,15-dienyl]-((R)-1-phenyl-ethyl)-carbamic acid tert-butyl ester [(E)-(2S,4R,8R,9S,11R)-8-(tert-Butyl-dimethyl-silanyloxy)-9-(4-methoxy-benzyloxy)-2,4,11-trimethyl-5,13-dioxo-tridec-6-enyl]-((R)-1-phenyl-ethyl)-carbamic acid tert-butyl ester