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(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

CAS号：334972-51-9

英文名：(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

分子式：C21H37BrO2Si

分子量：429.507

合成路线

374901-01-6

(R)-5-[2-(4-Methoxy-benzyloxy)-eth-(Z)-ylidene]-2-[(S)-2-phenylsulfanyl-1-(tetrahydro-pyran-2-yloxymethyl)-ethyl]-tetrahydro-pyran

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

374901-04-9

Triisopropyl-((S)-2-{(R)-5-[2-(4-methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-3-phenylsulfanyl-propoxy)-silane

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

334972-43-9

(S)-5-(tert-Butyldimethylsilyloxy)-4-(4-methoxybenzyloxy)pentanal

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

334972-54-2

(S)-tert-butyl((2-((4-methoxybenzyl)oxy)hex-5-en-1-yl)oxy)dimethylsilane

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

334972-47-3

(R)-2-[(2'R,5'S)-5'-(4-Methoxybenzyloxy)tetrahydropyran-2'-yl]-6-methylhept-5-enal

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

334972-49-5

(R)-2-[(1'S,2'R,5'R)-1'-(tert-Butyldimethylsilyloxy)-5'-(1-methylethenyl)-2'-cyclopentyl]tetrahydropyran-5-one

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

334972-46-2

Ethyl (R)-2-[(2'R,5'S)-5'-(4-methoxybenzyloxy)tetrahydropyran-2'-yl]-6-methylhept-5-enoate

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

374900-89-7

(R)-2-{(R)-5-[2-(4-Methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-3-triisopropylsilanyloxy-propan-1-ol

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

374901-05-0

Triisopropyl-((S)-2-{(R)-5-[2-(4-methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-6-methyl-hept-5-enyloxy)-silane

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

374900-96-6

(1S,2R,5S)-2-Isopropenyl-5-{(R)-5-[2-(4-methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-cyclopentanol

334972-51-9

(1S,2R,5R)-2-[(2'R,5'Z)-5'-(2''-Bromoethylidene)-tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

上游原料

(R)-2-[(2'R,5'S)-5'-(4-Methoxybenzyloxy)tetrahydropyran-2'-yl]-6-methylhept-5-enal Ethyl (R)-2-[(2'R,5'S)-5'-(4-methoxybenzyloxy)tetrahydropyran-2'-yl]-6-methylhept-5-enoate (1S,2R,5S)-2-Isopropenyl-5-{(R)-5-[2-(4-methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-cyclopentanol (S)-tert-butyl((2-((4-methoxybenzyl)oxy)hex-5-en-1-yl)oxy)dimethylsilane (R)-2-{(R)-5-[2-(4-Methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-3-triisopropylsilanyloxy-propan-1-ol (S)-2-{(R)-5-[2-(4-Methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-3-triisopropylsilanyloxy-propan-1-ol Triisopropyl-((S)-2-{(R)-5-[2-(4-methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-3-phenylsulfanyl-propoxy)-silane (R)-2-[(1'S,2'R,5'R)-1'-(tert-Butyldimethylsilyloxy)-5'-(1-methylethenyl)-2'-cyclopentyl]tetrahydropyran-5-one (S)-5-(tert-Butyldimethylsilyloxy)-4-(4-methoxybenzyloxy)pentanal (1S,2S,5R)-2-[(2'R,5'S)-5'-(4-Methoxybenzyloxy)tetrahydropyran-2'-yl]-5-(1-methylethenyl)cyclopentanol Triisopropyl-((S)-2-{(R)-5-[2-(4-methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-6-methyl-hept-5-enyloxy)-silane (R)-5-[2-(4-Methoxy-benzyloxy)-eth-(Z)-ylidene]-2-[(S)-2-phenylsulfanyl-1-(tetrahydro-pyran-2-yloxymethyl)-ethyl]-tetrahydro-pyran (R)-2-{(R)-5-[2-(4-Methoxy-benzyloxy)-eth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-6-methyl-hept-5-enal (1S,2R,5R)-2-[(2'R,5'S)-5'-(4-Methoxybenzyloxy)tetrahydropyran-2'-yl]-1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane

下游产品

(1S,1'S,2R,2'R,5R,5'R)-2,2'-{5,5'-[(R,S)-2-Phenylsulfonylbutane-1,4-diylidene]bis[(2R,5Z)-tetrahydropyran-2-yl]}bis[1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane] (1S,1'S,2R,2'R,5R,5'R)-2,2'-{5,5'-[Butane-1,4-diylidene]bis[(2R,5Z)-tetrahydropyran-2-yl]}bis[1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane] (1S,1'S,2R,2'R,5R,5'S)-2,2'-{5,5'-[(R,S)-2-Phenylsulfonylbutane-1,4-diylidene]bis[(2R,5Z)-tetrahydropyran-2-yl]}bis[1-(tert-butyldimethylsilyloxy)-5-(1-methylethenyl)cyclopentane]